Laboratory Autoclaves & Sterilizers

Authorized Yamato Scientific Dealer · Ships From US Inventory

Steam autoclaves, sterilizers with integrated dryer, and dry-heat sterilizers — 18 L benchtop through 110 L floor-standing, with validated, repeatable cycles.

Also ShopAutoclave AccessoriesLaboratory OvensGlassware WashersAll Equipment
ShopWhich TypeCompareWhy YamatoFAQ
Benchtop & Floor-Standing

Shop Yamato Autoclaves & Sterilizers

Across the range — from an 18 L benchtop unit to a 110 L high-throughput floor model.

Yamato SK102C compact steam autoclave 18LSK102C Compact Autoclave, 18 L$2,710.00Benchtop steam · top-loading Yamato SK401 natural convection dry sterilizer 99LSK401 Dry Sterilizer, 99 L$4,095.00Dry heat · moisture-sensitive loads Yamato SK301C compact steam autoclave 30LSK301C Compact Autoclave, 30 L$4,780.00Benchtop steam · larger loads Yamato SM301 steam sterilizer with dryer 32LSM301 Sterilizer + Dryer, 32 L$10,055.00Loads come out dry Yamato SN500C steam sterilizer 47LSN500C Sterilizer, 47 L$11,800.00Multi-course · instruments, liquids, media Yamato SQL1010C large capacity sterilizer 110LSQL1010C Sterilizer, 110 L$34,165.00High-throughput floor-standing
Which Type

Four Ways to Sterilize

Steam for most instruments, liquids and media; dry heat for anything moisture would ruin.

Compact Steam Autoclaves — SK

Top-loading benchtop units, 18–30 L, for instruments and small glassware loads. The economical, space-saving choice where bench space is the constraint.

SK102C, 18 L →

Steam + Integrated Dryer — SM

High-pressure steam plus a 150–180°C drying cycle, 20–80 L, so wrapped instruments and glassware come out dry and ready to use.

SM301, 32 L →

Steam, Multi-Course — SN / SQ / SQL

Large-capacity programmable autoclaves, 32–110 L, with instrument, liquid, media-melt and keep-warm courses for mixed daily workloads.

SN500C, 47 L →

Dry-Heat Sterilizers — SK

Hot-air sterilization, 99–300 L, for powders, oils, and moisture-sensitive items and glassware where steam is not suitable.

SK401, 99 L →

Compare

Model Comparison

Model Method Capacity Best for Price
SK102C Compact steam 18 L Benchtop instruments $2,710.00
SK401 Dry heat 99 L Moisture-sensitive items $4,095.00
SK301C Compact steam 30 L Larger benchtop loads $4,780.00
SM301 Steam + dryer 32 L Loads that must come out dry $10,055.00
SN500C Steam, multi-course 47 L Instruments, liquids, media $11,800.00
SQ810C Large-capacity steam 80 L Busy shared labs $17,180.00
SQL1010C Large-capacity steam 110 L High-throughput labs $34,165.00

Still deciding? Read the Autoclave & Sterilizer Buying Guide for a full steam-vs-dry-heat comparison, or browse baskets, racks and replacement parts.

Why Yamato

Validated, Repeatable Cycles

Operator Safety

Lid interlocks, pressure-relief valves and self-diagnostics on every model.

Programmable Courses

Instrument, liquid, media-melt and keep-warm cycles for mixed workloads.

To 135°C / 0.255 MPa

Full sterilization temperature and pressure on the larger chambers.

Manufacturer-Direct Support

Sizing and validation questions go straight to Yamato's own specialists.

Good to Know

Autoclave & Sterilizer FAQs

Steam or dry heat — which do I need?

Steam sterilization suits most instruments, liquids, and culture media, and works at lower temperatures in less time. Dry heat is for items steam would damage or cannot penetrate — powders, oils, greases, and certain glassware. Many labs run a steam autoclave as the primary unit and add a dry-heat sterilizer for the exceptions.

Do I need a model with a dryer?

Choose an SM series with the integrated drying cycle if wrapped instruments or glassware must come out dry and ready to use immediately. If you can air-dry loads, an SN, SQ or SQL without the dryer covers the same sterilization at lower cost.

What capacity should I buy?

Size to your peak load, not your average. An 18–30 L benchtop unit suits a single bench or small clinic; 47–80 L fits a busy shared lab; 110 L is for high-throughput operations running multiple cycles a day. Tell us your typical load and we will size it with you.

Can these sterilize liquids and culture media?

Yes — the multi-course SN, SQ and SQL models include dedicated liquid and media-melt programs, plus keep-warm for agar. Match the course to the load rather than running everything on the instrument cycle.

How do these ship, and are they genuine?

LabSupplies.com is an authorized Yamato Scientific dealer, so every unit is factory-sealed with the full manufacturer warranty intact. Benchtop autoclaves ship parcel from US inventory; the larger floor-standing chambers ship by freight, confirmed before you are charged.

28 products