CryoSure® Cryogenic Vial Screw Caps — HDPE, Yellow, 1000/Bag (300-3900-Y2K)
These yellow High-Density Polyethylene screw caps are purpose-built for CryoSure® cryogenic vials, rated for both LN₂ vapor phase and full LN₂ immersion storage down to -196°C as well as -80°C mechanical freezer archiving. Supplied in a 1000/Bag bulk format under part number 300-3900-Y2K, they follow the CLSI H3 SPS/ACD color convention — yellow designates blood culture and ACD-preserved cryogenic specimens — making them an efficient choice for high-throughput biobank and clinical biorepository programs that rely on color-coded specimen routing.
Technical Specifications
| Specification | Value |
|---|---|
| Part Number (MPN) | 300-3900-Y2K |
| Sub-brand | CryoSure® (Caplugs® Evergreen) |
| Cap Type | Screw Cap |
| Material | High-Density Polyethylene (HDPE) |
| Color | Yellow |
| Cryogenic Rating | LN₂ vapor phase and immersion (-196°C) |
| Mechanical Freezer Storage | -80°C |
| Autoclave Compatibility | 121°C / 15 psi |
| Pack Size | 1000/Bag |
| BPA / Phthalates | BPA-free; no phthalate plasticizers |
| Country of Origin | USA (California) |
Applications
- Biobank archiving programs using yellow color-designated cryogenic vials for ACD-preserved or blood culture specimens (CLSI H3 convention)
- Long-term cell line cryopreservation in DMSO-containing cryoprotectant media at LN₂ temperatures
- -80°C mechanical freezer biorepository storage of clinical and research specimens
- Multi-specimen cryobox programs that rely on color-coded cap systems for fast, error-resistant specimen retrieval
- Hospital and reference laboratory specimen archiving requiring autoclavable cap components for workflow flexibility
Compatibility
These caps are designed to fit CryoSure® cryogenic vials and are engineered specifically for LN₂ archive service — standard HDPE tube caps should not be substituted at LN₂ temperatures. Laboratories that want to verify fit and routing protocol before committing to bulk quantities can order the companion 200-count trial format (300-3900-Y20), which provides the same yellow HDPE cap in a smaller pack size. Once fit is confirmed, the 1000/Bag format offers a lower per-cap cost for ongoing institutional consumption.
Chemical Resistance
| Reagent / Condition | Compatibility |
|---|---|
| Liquid nitrogen — vapor phase and immersion (-196°C) | Excellent — engineered for LN₂ service |
| Mechanical freezer storage (-80°C) | Excellent |
| Aqueous cryoprotectants (FBS, glycerol, Bambanker) | Excellent |
| DMSO at standard cryo concentrations (5–10%) | Good |
| Autoclave (121°C / 15 psi) | Compatible |
| Concentrated organic solvents | Not recommended |
Quality & Procurement
Made in USA at Caplugs® Evergreen's California manufacturing facility, these CryoSure® caps are precision-molded from BPA-free, phthalate-free HDPE resin under ISO 9001 quality management. LabSupplies.com is an authorized Caplugs® Evergreen dealer stocking USA inventory, with tiered pricing available for reference laboratories, hospital systems, biobanks, and grant-funded research programs.
Frequently Asked Questions
Are these caps rated for direct LN₂ immersion, or only vapor phase?
They are rated for both LN₂ vapor phase and full LN₂ immersion storage down to -196°C, as well as -80°C mechanical freezer archiving. Standard HDPE caps not specifically designed for cryogenic service should not be used as substitutes at these temperatures.
What does the yellow color signify in a lab setting?
Yellow CryoSure® caps correspond to the CLSI H3 SPS/ACD color convention, designating blood culture and ACD-preserved cryogenic specimens. In multi-specimen cryobox programs, consistent color coding allows fast, error-resistant specimen identification without relabeling.
Can I use these caps with DMSO-based cryoprotectant media?
Yes — HDPE shows good compatibility with DMSO at standard cryopreservation concentrations (5–10%), making these caps suitable for cell line archives prepared in DMSO-containing freeze media. Concentrated organic solvents are not recommended.
Is there a smaller pack size available to verify fit before ordering 1000 caps?
Yes — the 300-3900-Y20 is the same yellow HDPE CryoSure® cap supplied in a 200/Bag format, allowing you to confirm thread fit and color-routing protocols before committing to the full 1000/Bag quantity.