CryoSure® Cryogenic Vial Screw Caps — HDPE, White, 200/Bag (300-3900-W20)
These white high-density polyethylene screw caps are purpose-built for CryoSure® cryogenic vials, rated for storage across the full cryogenic range from –80°C mechanical freezers through liquid nitrogen vapor phase and immersion at –196°C. Supplied as part number 300-3900-W20 in 200/Bag, white is the preferred color choice for biorepository programs that rely on adhesive or LIS-printed barcode labels, since HDPE white delivers the highest-contrast surface for both direct-print and adhesive label readability. HDPE construction also provides autoclave compatibility at 121°C, making these caps suitable for pre-sterilization workflows.
Technical Specifications
| Specification | Value |
|---|---|
| Part Number (MPN) | 300-3900-W20 |
| Sub-brand | CryoSure® (Caplugs® Evergreen) |
| Cap Type | Screw Cap |
| Material | High-Density Polyethylene (HDPE) |
| Color | White |
| Cryogenic Rating | LN₂ vapor phase and immersion (–196°C) |
| Freezer Storage | –80°C mechanical freezer compatible |
| Autoclave Compatibility | 121°C / 15 psi |
| Pack Size | 200/Bag |
| BPA / Phthalates | BPA-free; no phthalate plasticizers |
| Country of Origin | USA (California) |
Applications
- Biobank and biorepository archiving: capping CryoSure® cryogenic vials for long-term LN₂ vapor-phase or immersion storage
- –80°C mechanical freezer programs for clinical specimens, plasma, serum, and tissue biopsies
- Cell line cryopreservation using DMSO-based cryoprotective media at standard working concentrations (5–10%)
- LIS-integrated specimen tracking programs where white cap surfaces maximize barcode label contrast and scanner read rates
- Color-coded multi-specimen cryogenic box programs requiring a white designation across CryoSure® vial sets
- Pre-sterilization workflows requiring autoclavable cryovial closures
Compatibility
These caps are designed specifically to fit CryoSure® cryogenic vials and use the CryoSure® grade thread geometry engineered to maintain a secure seal through repeated freeze-thaw cycles, including LN₂ immersion conditions. Standard HDPE tube caps not rated for cryogenic service should not be substituted at LN₂ temperatures; CryoSure® caps are formulated and tested for cryo-toughness across the full –196°C to +121°C service range. White is available in the 200/Bag pack size; laboratories requiring larger volumes in other colors can choose from the broader CryoSure® cap range, which includes Natural, Blue, Dark Green, Orange, Green, Lavender, Red, Yellow, and additional 1000/Bag formats.
Chemical Resistance
| Reagent / Condition | Compatibility |
|---|---|
| Liquid nitrogen (–196°C) — vapor phase | Excellent — engineered for LN₂ service |
| Liquid nitrogen (–196°C) — immersion | Excellent — engineered for LN₂ service |
| –80°C mechanical freezer storage | Excellent — HDPE cryo-toughened |
| DMSO (5–10% cryoprotectant concentration) | Good — standard cryo media compatible |
| Aqueous cryoprotectants (FBS, glycerol, Bambanker) | Excellent |
| Aqueous buffers and saline | Excellent |
| Autoclave (121°C / 15 psi) | Compatible |
| Concentrated organic solvents | Not recommended |
Quality & Procurement
Made in USA at Caplugs® Evergreen's California manufacturing facility, these CryoSure® caps are precision-molded from BPA-free, phthalate-free HDPE resin under ISO 9001 quality management. LabSupplies.com is an authorized Caplugs® Evergreen dealer shipping from USA inventory, with tiered institutional pricing available for hospitals, reference laboratories, biotech companies, and grant-funded research programs.
Frequently Asked Questions
Are these caps rated for liquid nitrogen immersion, or only vapor-phase storage?
CryoSure® caps, including the white 300-3900-W20, are rated for both LN₂ vapor-phase storage at –196°C and direct LN₂ immersion. The HDPE formulation is specifically cryo-toughened to maintain thread integrity and a secure seal under immersion conditions, unlike standard HDPE tube caps not rated for cryogenic service.
Why choose white caps over natural (clear) or a colored option?
White provides the highest-contrast background for adhesive labels and LIS-printed barcodes, making it the preferred choice for automated biorepository routing systems where label readability directly drives specimen identification. If your program uses cap color as the primary specimen-type or cohort designator instead, the CryoSure® range offers eleven additional color options.
Can these caps be autoclaved before use?
Yes — HDPE CryoSure® caps are compatible with standard autoclave cycles at 121°C / 15 psi, supporting pre-sterilization workflows before cryovial filling and archiving.
Are these caps compatible with DMSO-based cryoprotective media?
Yes, at standard cryopreservation working concentrations of 5–10% DMSO these caps perform well. Concentrated neat DMSO or other concentrated organic solvents are not recommended for prolonged contact with HDPE.