Caplugs® Evergreen
Cryo Vial Caps, Screw Caps, HDPE, Blue — 300-3900-B20 | 200/Bag | Caplugs® Evergreen
Cryo Vial Caps, Screw Caps, HDPE, Blue — 300-3900-B20 | 200/Bag | Caplugs® Evergreen
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CryoSure® Cryogenic Vial Caps, HDPE, Blue — 300-3900-B20 | 200/Bag
| Quick Reference — 300-3900-B20 | |
|---|---|
| Sub-brand | CryoSure® (Caplugs® Evergreen) |
| Cap Type | Screw cap — cryogenic vial thread |
| Material | High-Density Polyethylene (HDPE) |
| Color | Blue |
| Cryo Rating | ✓ LN₂ vapor phase (-196°C) and immersion |
| Cryo Storage | ✓ -80°C ultra-low temp and -196°C LN₂ |
| Color Use | Blue caps mirror the CLSI H3 blue-top citrate convention — d |
| Pack Size | 200/Bag |
| Price | $17.71 / Bag ($0.0886 / cap) |
Technical Narrative
The Caplugs® Evergreen CryoSure® is a blue HDPE screw cap for CryoSure® cryogenic vials — engineered specifically for cryogenic biorepository storage at liquid nitrogen vapor phase (-196°C) and immersion temperatures, and ultra-low temperature mechanical freezers (-80°C). Standard HDPE tube caps from the 300-3010/300-3532/300-3541 families are rated for -80°C storage; CryoSure® caps extend the cryo rating to -196°C LN₂ — the additional engineering required for the extreme thermal contraction at liquid nitrogen temperatures that can fracture standard HDPE thread geometry and allow cryoprotectant evaporation loss over long-term LN₂ archive. Blue caps mirror the CLSI H3 blue-top citrate convention — designating citrate-preserved biobank specimens in CryoSure® vial cryo archives.
HDPE CryoSure® caps combine the chemical resistance required for cryogenic vial applications — DMSO cryoprotectant at standard concentrations (5–10%), freezing media (FBS, glycerol, Bambanker), and standard biobank buffer formulations — with autoclave compatibility at 121°C for pre-sterilized cap supply. The 200/Bag format is the trial-size entry point for laboratories evaluating CryoSure® caps before committing to bulk 1000-count orders — available for all nine colors at $17.71/bag.
At $17.71 per 200/Bag — $0.0886 per cap. Bulk 1000/Bag packs available for selected colors: 300-3900-DG2K (Dark Green, 1000/Bag); 300-3900-G2K (Green, 1000/Bag); 300-3900-R2K (Red, 1000/Bag). See the complete color table above.
Technical Specifications — Caplugs® Evergreen
| Specification | Value |
|---|---|
| Part Number | |
| Caplugs Item # | 3003900B20E1 |
| Sub-brand | CryoSure® (Caplugs® Evergreen) |
| Cap Style | Screw cap — CryoSure® vial thread |
| Material | High-Density Polyethylene (HDPE) |
| Color | Blue |
| Cryo Rating | LN₂ vapor phase and immersion (-196°C) |
| Cryo Storage | ✓ -80°C and -196°C compatible |
| Autoclave | ✓ Compatible (121°C / 15 psi) |
| Pack Size | 200/Bag |
| BPA/Phthalate | BPA-free; no phthalate plasticizers |
| Country of Origin | Made in U.S.A. (California) |
CryoSure® Cryogenic Vial Cap Application Compatibility
CryoSure® caps fit CryoSure® cryogenic vials for:
| Application | Use / Storage | Notes |
|---|---|---|
| Cryogenic vial capping | CryoSure® cryogenic vials (Caplugs® Evergreen) | HDPE cap engineered for -196°C LN₂ vapor phase storage |
| Liquid nitrogen vapor storage | Biobank LN₂ vapor phase archive at -196°C | HDPE cryo-toughened for vapor phase cycling without cap fracture |
| LN₂ immersion storage | Liquid nitrogen immersion cryogenic archive | HDPE resists direct LN₂ liquid phase contact |
| -80°C mechanical freezer | Ultra-low temperature biorepository -80°C | HDPE maintains thread engagement through -80°C cycling |
| Biobank specimen archiving | Blood, tissue, cell line biobank caps | Color-coded caps enable visual specimen-type routing in cryo boxes |
| Color-coded cryo routing | Multi-specimen cryo box organization | 9 cap colors map to specimen type, donor cohort, or date batch |
| Long-term archive replacement | Replacing caps on existing cryo vials | 200/Bag trial size and 1000/Bag bulk formats available |
| Clinical biorepository | Hospital biobank, transplant program tissue bank | HDPE CLSI-convention colors for clinical specimen routing |
Always validate cap-to-vial thread fit with a sample. CryoSure® caps are specifically engineered for LN₂ temperatures — do not substitute standard HDPE tube caps for LN₂ archive.
Chemical Resistance — High-Density Polyethylene (HDPE) — CryoSure® Grade
CryoSure® HDPE maintains thread integrity and chemical resistance from +121°C autoclave through -196°C LN₂.
| Reagent / Condition | Compatibility |
|---|---|
| Liquid nitrogen (-196°C) | ✓ CryoSure® grade — vapor and immersion phase |
| Storage at -80°C | ✓ Excellent — HDPE cryo-toughened |
| Aqueous buffers / cryoprotectants | ✓ Excellent |
| DMSO (cryoprotectant) | ✓ Good — standard cryo media concentration |
| Short-chain alcohols | ✓ Good |
| Autoclave (121°C) | ✓ Compatible |
| Concentrated organic solvents | ✗ Not recommended |
Complete CryoSure® Cap Color Range
All colors identical HDPE cryo specification. 200/Bag trial packs and 1000/Bag bulk packs available for selected colors:
| Part Number | Color | Pack | Price |
|---|---|---|---|
| 300-3900-020 | Natural | 200/Bag | $17.71 |
| Blue | 200/Bag | $17.71 | |
| 300-3900-DG2K | Dark Green | 1000/Bag | $81.98 |
| 300-3900-E20 | Orange | 200/Bag | $17.71 |
| 300-3900-G20 | Green | 200/Bag | $17.71 |
| 300-3900-G2K | Green | 1000/Bag | $84.87 |
| 300-3900-L20 | Lavender | 200/Bag | $17.71 |
| 300-3900-R20 | Red | 200/Bag | $17.71 |
| 300-3900-R2K | Red | 1000/Bag | $84.87 |
| 300-3900-W20 | White | 200/Bag | $17.71 |
| 300-3900-Y20 | Yellow | 200/Bag | $17.71 |
| 300-3900-Y2K | Yellow | 1000/Bag | $84.87 |
Laboratory Applications
CryoSure® serves biobank and biorepository programs archiving cryogenic vials in LN₂ vapor phase and immersion; cell biology programs cryopreserving cell lines with DMSO; clinical biorepository programs (transplant tissue banks, cord blood banks, fertility clinics); and any program requiring color-coded HDPE cryo vial caps rated for -196°C LN₂ storage.
U.S. Manufacturing, Quality & Institutional Procurement
Every Caplugs® Evergreen lot is precision-molded at our California manufacturing facility. We supply reference laboratories, hospital systems, and federal procurement offices under institutional pricing programs. Request a free sample below to validate fit before committing to volume.
Frequently Asked Questions — Caplugs® Evergreen
What is the difference between CryoSure® caps and standard HDPE tube caps?
Standard Caplugs® Evergreen HDPE caps (300-3010, 300-3532, 300-3541) are rated for -80°C ultra-low temperature storage. CryoSure® caps (300-3900) are engineered specifically for cryogenic vial applications at -196°C liquid nitrogen vapor phase and immersion — the additional 50 °C difference from -80°C to -196°C is significant: standard HDPE thread geometry can fracture under the extreme thermal contraction at LN₂ temperatures, allowing cryoprotectant vapor loss over long-term archive. CryoSure® caps are specifically engineered to maintain thread engagement and sealing integrity at LN₂ temperatures.
What is the difference between the 200/Bag and 1000/Bag CryoSure® cap formats?
200/Bag packs (e.g., 300-3900-020, -B20, -E20) are the trial-size format — $17.71/bag ($0.0886/cap) — suited for evaluating color routing before bulk ordering, or for low-volume programs requiring a small stock of multiple colors. 1000/Bag bulk packs (e.g., 300-3900-DG2K, -G2K, -R2K, -Y2K) are available for selected colors at approximately $0.082/cap — a ~7% per-cap savings over 200-count bags for high-volume programs.
Are CryoSure® caps compatible with DMSO cryoprotectant at freezing concentrations?
Yes. HDPE CryoSure® caps are compatible with DMSO at standard cryoprotection concentrations (typically 5–10% DMSO in freezing media). HDPE maintains chemical resistance to DMSO across the full temperature range from room temperature cell suspension preparation through controlled-rate freezing to LN₂ storage and thaw. For unusual DMSO concentrations above 10%, validate compatibility before committing to bulk cap supply.
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