CryoSure® Cryogenic Vial Screw Caps — HDPE, Blue, 200/Bag (300-3900-B20)
These blue HDPE screw caps from the Caplugs® Evergreen CryoSure® line are engineered for long-term cryogenic biorepository storage, rated for both liquid nitrogen vapor phase and immersion temperatures down to -196°C as well as ultra-low temperature mechanical freezers at -80°C. Supplied 200 per bag, part number 300-3900-B20 is the trial-size entry point for laboratories evaluating CryoSure® caps before committing to bulk quantities. The blue color follows the CLSI H3 blue-top citrate convention, enabling consistent visual routing of citrate-preserved biobank specimens across cryo boxes and LN₂ archives.
Technical Specifications
| Specification | Value |
|---|---|
| Part Number (MPN) | 300-3900-B20 |
| Sub-brand | CryoSure® (Caplugs® Evergreen) |
| Cap Style | Screw Cap — CryoSure® Vial Thread |
| Material | High-Density Polyethylene (HDPE) |
| Color | Blue |
| Cryogenic Rating | LN₂ vapor phase and immersion (-196°C) |
| Ultra-Low Temp Storage | -80°C compatible |
| Autoclave Compatibility | 121°C / 15 psi |
| Pack Size | 200/Bag |
| BPA / Phthalates | BPA-free; no phthalate plasticizers |
| Country of Origin | USA (California) |
Applications
- Capping CryoSure® cryogenic vials for long-term LN₂ vapor phase archive at -196°C, where standard HDPE thread geometry would risk fracture and cryoprotectant evaporation loss
- LN₂ immersion cryogenic storage — HDPE resists direct liquid nitrogen contact through extended archive cycles
- Ultra-low temperature (-80°C) mechanical freezer biorepository storage, with maintained thread engagement through repeated thermal cycling
- Biobank specimen archiving of blood, tissue, and cell line samples, with blue color designating citrate-preserved specimens per the CLSI H3 convention
- Color-coded cryo box organization — mapping cap color to specimen type, donor cohort, or date batch across multi-specimen archives
- Replacement capping of existing cryogenic vials requiring a cryo-rated HDPE screw cap
Compatibility
The 300-3900-B20 caps are designed to fit CryoSure® cryogenic vials from Caplugs® Evergreen. Unlike standard HDPE tube caps in the 300-3010, 300-3532, and 300-3541 families — which are rated for -80°C storage — CryoSure® caps are specifically engineered to withstand the extreme thermal contraction at liquid nitrogen temperatures (-196°C) that can fracture standard HDPE thread geometry. Laboratories replacing caps on existing CryoSure® vials or stocking replacement caps for ongoing biobank programs should verify that the vial thread matches the CryoSure® cap thread before ordering. Bulk 1000/Bag packs are available for selected colors, including Dark Green (300-3900-DG2K), Green (300-3900-G2K), and Red (300-3900-R2K).
Chemical Resistance
| Reagent / Condition | Compatibility |
|---|---|
| DMSO cryoprotectant (5–10% standard concentrations) | Compatible |
| Freezing media (FBS, glycerol, Bambanker) | Compatible |
| Standard biobank buffer formulations | Compatible |
| Aqueous buffers / saline | Excellent |
| Dilute acids and bases | Good |
| Chlorinated / aromatic solvents | Not recommended |
Quality & Procurement
Made in USA (California), these CryoSure® caps are produced under ISO 9001 quality management from BPA-free, phthalate-free HDPE resin, and are autoclave-compatible at 121°C for laboratories requiring pre-sterilized cap supply. LabSupplies.com is an authorized Caplugs® Evergreen dealer and ships from USA inventory, with the 200/Bag format serving as a cost-effective evaluation quantity before transitioning to bulk 1000-count orders. Tiered pricing is available for institutional, grant-funded, and high-volume biobank procurement programs.
Frequently Asked Questions
What makes these caps different from standard HDPE screw caps rated for -80°C?
CryoSure® caps are specifically engineered to withstand the extreme thermal contraction that occurs at liquid nitrogen temperatures (-196°C). Standard HDPE screw caps — such as those in the 300-3010, 300-3532, and 300-3541 families — are rated only to -80°C; at LN₂ temperatures, standard HDPE thread geometry can fracture and allow cryoprotectant evaporation loss during long-term archive storage.
Are these caps autoclavable?
Yes — HDPE CryoSure® caps are autoclave-compatible at 121°C / 15 psi, making them suitable for laboratories that require pre-sterilized cap supply before use in sterile biobank workflows.
Why are the caps blue, and does the color serve a functional purpose?
Blue mirrors the CLSI H3 blue-top citrate tube convention, allowing biorepository staff to visually designate citrate-preserved specimens in cryo boxes and LN₂ archives without additional labeling. CryoSure® caps are available in nine colors total, enabling color-coded routing by specimen type, donor cohort, or date batch.
Can these caps be used with cryogenic vials from other manufacturers?
These caps are designed for CryoSure® cryogenic vials from Caplugs® Evergreen. Thread geometry varies between vial manufacturers, so compatibility with third-party vials is not guaranteed. Always verify the vial thread profile matches the CryoSure® cap thread before substituting from another supplier.