CryoSure® Cryogenic Vial Screw Caps — HDPE, Natural, 200/Bag (300-3900-020)
These natural High-Density Polyethylene screw caps are engineered specifically for CryoSure® cryogenic vials, delivering reliable thread engagement at temperatures ranging from –80°C ultra-low mechanical freezers down to –196°C liquid nitrogen vapor phase and immersion storage. Unlike standard HDPE tube caps, the CryoSure® design accommodates the extreme thermal contraction experienced at liquid nitrogen temperatures — preventing thread fracture and cryoprotectant evaporation loss during long-term biorepository archiving. The natural color makes these caps a universal choice compatible with any labeling system, and the 200/Bag pack size is an ideal entry point for laboratories evaluating CryoSure® caps before committing to bulk quantities.
Technical Specifications
| Specification | Value |
|---|---|
| Part Number (MPN) | 300-3900-020 |
| Sub-brand | CryoSure® (Caplugs® Evergreen) |
| Cap Style | Screw cap — CryoSure® vial thread |
| Material | High-Density Polyethylene (HDPE) |
| Color | Natural |
| Cryogenic Rating | LN₂ vapor phase and immersion (–196°C) |
| Ultra-Low Temp Storage | Compatible (–80°C) |
| Autoclave Compatibility | 121°C / 15 psi |
| BPA / Phthalates | BPA-free; no phthalate plasticizers |
| Pack Size | 200/Bag |
| Country of Origin | USA (California) |
Applications
- Capping CryoSure® cryogenic vials for long-term liquid nitrogen vapor phase archive at –196°C
- Direct LN₂ immersion storage where HDPE thread geometry must withstand liquid-phase contact without fracture
- Ultra-low temperature (–80°C) mechanical freezer biorepositories requiring secure thread engagement through repeated freeze-thaw cycling
- Biobank specimen archiving for blood, tissue, and cell line samples, with natural color accommodating any labeling or color-coding workflow
- Multi-specimen cryo box organization — natural caps serve as a universal baseline when color-coded routing by specimen type, donor cohort, or date batch is not required
- Replacement capping of existing cryogenic vials in established biorepository programs
Compatibility
These caps are designed to fit CryoSure® cryogenic vials from Caplugs® Evergreen and are threaded specifically for the CryoSure® vial format. Laboratories managing mixed cryo box inventories should verify thread compatibility with their existing vial stock before transitioning from OEM supply. For programs requiring color-coded specimen routing, CryoSure® caps are available in nine colors — all sharing the same CryoSure® thread geometry — so a confirmed fit on any one color confirms fit across the full color family.
Chemical Resistance
| Reagent / Condition | Compatibility |
|---|---|
| DMSO cryoprotectant (5–10%) | Good — suitable for standard cryogenic concentrations |
| Freezing media (FBS, glycerol, Bambanker) | Good |
| Aqueous biobank buffers / saline | Excellent |
| Dilute acids and bases | Good |
| Alcohols (short-term contact) | Good |
| Chlorinated / aromatic solvents | Not recommended |
Quality & Procurement
Made in USA (California), these CryoSure® caps are manufactured under ISO 9001 quality management from BPA-free, phthalate-free HDPE resin — the same cryogenic-grade material formulation engineered to resist brittle fracture under extreme thermal contraction at liquid nitrogen temperatures. Autoclave compatibility at 121°C / 15 psi supports pre-sterilized cap supply workflows for BSL and GMP environments. LabSupplies.com is an authorized Caplugs® Evergreen dealer shipping from USA inventory, with the 200/Bag format available for all nine CryoSure® cap colors and bulk 1000/Bag packs offered for selected colors.
Frequently Asked Questions
Are these caps rated for direct liquid nitrogen immersion, or only vapor phase storage?
They are rated for both — LN₂ vapor phase at –196°C and direct liquid nitrogen immersion. The CryoSure® thread geometry is specifically engineered to resist the extreme thermal contraction that can fracture standard HDPE caps at liquid nitrogen temperatures, making these suitable for either storage mode.
Can these caps be autoclaved before use?
Yes. These caps are autoclave-compatible at 121°C / 15 psi, allowing laboratories to pre-sterilize cap supply for workflows requiring sterile cryogenic vial assemblies.
Will these caps fit standard cryogenic vials from other manufacturers?
Part number 300-3900-020 is designed for CryoSure® cryogenic vials from Caplugs® Evergreen. Thread dimensions on vials from other manufacturers may differ, so physical verification is recommended before substituting OEM caps in an established program.
Why choose natural over a color-coded cap?
Natural HDPE caps are the all-purpose default in the CryoSure® line — they accept any label, marker, or barcode system without color-coding constraints and integrate cleanly into programs where specimen routing is managed by label or LIS rather than cap color. Laboratories that do use color-coded routing can mix natural caps with the other eight available CryoSure® colors since all share the same thread geometry.