0.37 mL Microplates, Flat Bottom, PP, Natural, Beckman® Compatible — 290-8350-03F | 10/Box | Caplugs® Evergreen

96-Well Flat Bottom Microplates, 0.37 mL Well Volume, PP, Natural — 290-8350-03F | 10/Box (100/Case)

Technical Narrative

The Caplugs® Evergreen is a 96-well flat-bottom Polypropylene (PP) microplate — the DMSO-tolerant and autoclave-compatible alternative to the PS 96-well format for assay applications requiring broader chemical resistance. PP is compatible with DMSO at all concentrations — making it the 96-well format of choice for compound library source plates in acoustic dispensing programs, where compounds are stored as 10 mM or higher DMSO stocks that would stress-crack PS source plates over repeated dispensing cycles and freeze-thaw events. PP is also autoclave-compatible at 121°C, enabling pre-sterilization for cell culture applications where sterile plate supply is required.

The 0.37 mL flat-bottom geometry is identical to the PS 96-well standard (290-8115-01F) — all validated 96-well flat-bottom assay protocols transfer directly to PP format without geometry-driven method revalidation. PP's natural translucent finish is slightly less optically clear than PS, but sufficient for absorbance reads at 405–750 nm, visual cell assessment, and fluorescence intensity detection. For UV absorbance at 260–280 nm, the acrylic plate (290-8120-0AF) provides superior UV transmission. PP's broad resistance to chlorinated solvents, concentrated acids, detergents, and organic solvents makes it the 96-well format for chemically demanding extraction and lysis protocols.

At $120.33 per Box of 10 — $1.2033 per plate — the carries a modest premium over the PS variant (290-8115-01F, $120.33/box) that is justified whenever DMSO compound delivery, organic solvent exposure, or autoclave sterilization are workflow requirements.

Technical Specifications — Caplugs® Evergreen

PP 96-Well Flat Bottom Plate Workflow Compatibility — DMSO & Autoclave

PP 96-well flat-bottom plates extend the standard 96-well format with full DMSO compatibility and autoclave sterilization. Key advantages over PS:

PP plates are naturally translucent — suitable for most cell and assay monitoring. For quantitative UV absorbance reads, acrylic (290-8120-0AF) provides superior UV transmission. For standard ELISA and cell culture without DMSO/autoclave needs, PS flat-bottom (290-8115-01F) is the cost-effective choice.

Chemical Resistance — Polypropylene (PP)

PP provides the broadest chemical resistance of standard microplate polymers including full DMSO compatibility and autoclave compatibility.

Laboratory Applications

The serves pharmaceutical drug discovery programs using PP 96-well source plates for acoustic dispensing (Echo, Mosquito) of DMSO compound stocks; proteomics and biochemistry programs running organic solvent extraction in 96-well format; cell biology programs requiring autoclave-sterilized 96-well plates; immunoprecipitation protocols with RIPA or IP buffer lysis; lipid extraction and fatty acid quantification; and any 96-well assay where PS chemical resistance is a documented limitation.

U.S. Manufacturing, Quality & Institutional Procurement

Every Caplugs® Evergreen lot is precision-molded at our California manufacturing facility and subject to rigorous dimensional inspection and material purity verification. We supply reference laboratories, hospital systems, biotech firms, and federal procurement offices under institutional pricing programs with blanket-order support and same-day shipping on stocked inventory. Request a sample below to validate before committing to volume.

Frequently Asked Questions — Caplugs® Evergreen

When should I use PP 96-well instead of PS 96-well (290-8115-01F)?

Choose PP when your protocol involves: (1) DMSO at any concentration — PP is fully DMSO-resistant where PS degrades above ~10%; (2) Acoustic dispensing of DMSO compound stocks — PP withstands repeated DMSO exposure across full compound library plate cycling; (3) Autoclave sterilization before use; (4) Organic solvent extraction (chloroform, hexane, EtOAc); (5) Lysis buffers with high detergent content. For standard ELISA, colorimetric cell assays, and aqueous protocols, PS (290-8115-01F) is equivalent at lower cost per plate.

Is the PP 96-well plate compatible with acoustic dispensers (Echo, Mosquito)?

Yes. PP 96-well plates are the standard source plate format for acoustic liquid dispensers (Labcyte/Beckman Echo, SPT Labtech Mosquito) when handling DMSO compound stocks. The acoustic transducer ejects from each well, and PP resists the DMSO carrier solvent across the full compound library cycling lifetime. PS source plates can develop micro-cracks under repeated DMSO acoustic dispensing cycles. Confirm your specific dispenser's source plate specification — some instruments require specific PP plate geometries.

Are the PP 96-well plates BPA-free and autoclave-compatible?

Yes to both. The is molded from virgin Polypropylene (PP) containing no BPA and no phthalate plasticizers. PP is autoclave-compatible at 121°C / 15 psi. Leave PP plates uncovered during autoclaving to prevent pressure buildup.