Heathrow Scientific Microcentrifuge Tubes - HS4323 Series | DNase/RNase-Free, Autoclavable

Stop reaching for the wrong tube mid-protocol. Heathrow Scientific natural polypropylene microcentrifuge tubes (HS4422, HS4423, HS4323, HS4325) are engineered so that contamination, cap failure, and tube-to-tube variability are never the variable in your experiment. Certified DNase-free, RNase-free, and pyrogen-free from the factory, autoclavable for secondary sterilization, and rated to 16,400 × g — these tubes cover every routine spin-down, RNA extraction, enzyme aliquot, and PCR setup in the 0.2 mL, 0.5 mL, and 1.5 mL volumes that account for the vast majority of bench-scale molecular biology work. The attached snap cap closes one-handed and is syringe-pierceable, keeping your sample protected between aliquotting steps without opening the tube.

Features and Benefits

• Certified DNase-free, RNase-free, and pyrogen-free by lot — every production lot tested and documented; RNA-seq, RT-PCR, and endotoxin-sensitive applications run without tube-sourced contamination as a variable

• Attached snap cap, syringe-pierceable membrane — one-handed closure keeps both hands in the workflow; pierce the cap with a standard syringe needle (18G–26G) to aliquot without exposing sample contents to ambient contamination between draws

• Frosted writing area molded into the tube wall — write directly with a permanent marker or lab pencil without a separate label; frosting survives centrifuge cycles and freeze-thaw without flaking or peeling

• Autoclavable polypropylene — 121°C gravity cycle rated — steam-sterilize before use in sterility-critical applications; the polypropylene formulation withstands standard and pre-vacuum autoclave cycles without deformation

• Max RCF matched to real benchtop centrifuge speeds — 0.2 mL and 0.5 mL rated to 15,000 × g; 1.5 mL rated to 16,400 × g; covers the full speed range of Eppendorf, Thermo, and Heathrow Scientific Sprout microcentrifuges without cap ejection or tube failure

• Imprinted graduation markings for visual volume confirmation — 0.5 mL tube marked at 0.1, 0.3, 0.5 mL; 1.5 mL tube marked at 0.1, 0.5, 1.0 mL; reduces pipetting errors during serial dilutions and reaction master mix setup

• 1.5 mL available in pack of 500 or 1,000 — same per-unit price floor — pack/500 (HS4323, $21) for single-bench budgets and storage-limited spaces; pack/1,000 (HS4325, $19) for high-throughput labs where per-tube cost matters across tens of thousands of tubes per year

Specifications

Laboratory Applications

• PCR & qPCR Reaction Setup (0.2 mL) — the 0.2 mL format is the standard vessel for individual PCR reactions in thermal cycler blocks; the 15,000 × g rating handles the brief spin-down before cycling; the attached cap seals without deforming during thermocycling in single-reaction strip-free protocols

• Enzyme & Reagent Aliquoting (0.5 mL) — split restriction enzymes, ligases, and polymerases from stock vials into working aliquots; the syringe-pierceable cap enables closed-system aliquotting that preserves remaining freeze-thaw cycles on expensive enzymes

• Nucleic Acid Extraction & Column Cleanup (1.5 mL) — silica-column kits from Qiagen, Zymo, and Thermo produce eluates collected in 1.5 mL tubes; the 16,400 × g rating handles the high-speed binding and wash steps without tube deformation

• Cell Pelleting & Lysate Preparation (1.5 mL) — bacterial and mammalian cell pellets from small culture volumes collect at 6,000–12,000 × g; the translucent natural color allows visual confirmation of pellet formation without opening the tube

• Sample Archival & Biobank Storage (1.5 mL) — polypropylene is compatible with long-term storage at −80°C; the attached cap prevents the cap-loss failure mode common with separate-cap formats during repeated freeze-thaw cycling in active −80°C freezers

Frequently Asked Questions

Pack of 500 or pack of 1,000 for the 1.5 mL — what is the per-tube cost difference?
The pack/500 (HS4323) is $21 — $0.042 per tube. The pack/1,000 (HS4325) is $19 — $0.019 per tube. The 1,000-count pack cuts per-tube cost by more than half. For any lab using more than one pack per month, the pack/1,000 is the clear value choice. The pack/500 suits labs where bench storage space is limited or where a smaller trial quantity is preferred before committing to volume.

Are these tubes compatible with the Heathrow Scientific Sprout® microcentrifuge?
Yes. The 1.5 mL tubes (10.8 mm OD) fit the standard Sprout® and Sprout® Plus rotor directly. The 0.5 mL tubes require the appropriate adapter for the Sprout® rotor — verify your rotor model supports 0.5 mL before ordering. The 0.2 mL tubes are designed for 0.2 mL PCR tube rotor formats — confirm your Sprout® rotor accommodates 0.2 mL before use.

What does "syringe-pierceable cap" mean and how do I use it?
The snap cap membrane is thin enough to be penetrated by a standard syringe needle (18G to 26G) while maintaining a liquid-tight seal around the shaft during the draw. After the needle is withdrawn, the membrane self-seals. This allows repeated sampling from a stock aliquot tube without opening and recapping between draws — particularly useful for expensive enzymes or reagents where minimizing air exposure between uses matters.

Can I autoclave these tubes before use for sterile cell culture applications?
Yes. The polypropylene construction withstands standard gravity autoclave cycles at 121°C. Autoclaving does not add to the DNase/RNase-free factory certification — these tubes are already certified clean. Autoclave when sterility (freedom from viable organisms) is an additional requirement beyond nuclease-free performance, such as for certain cell culture or microinjection protocols.

Quality Assurance

Heathrow Scientific microcentrifuge tubes are manufactured under ISO-certified production controls. Each lot is certified DNase-free, RNase-free, and pyrogen-free with full documentation available for quality system and regulatory records. The syringe-pierceable cap membrane is tested for self-sealing integrity after repeated needle punctures at standard gauge sizes. Tubes ship in sealed bulk packs to maintain certification status.

Academic and Institutional Pricing

LabSupplies.com offers tiered quantity pricing for academic and research institutions. As an authorized dealer, we ship directly from USA inventory.