Surety® Column Fine-Filter Adapters, Midi 1.9″ — 2.4–3.5 mL, LDPE, Natural (208-3042-020)
These Caplugs® Evergreen Surety® Columns are molded in Low-Density Polyethylene (LDPE) and feature a fine-filter pore size of 15–45 microns, making them ideal for high-clarity filtrate preparation in SPE workflows that feed directly into sensitive downstream analytical detection. The Midi 1.9″ format accommodates a working capacity of 2.4–3.5 mL, pairing with 5 mL or 15 mL collection tubes for higher-sample-load applications. Supplied non-sterile in convenient 1000/Bag packaging, part number 208-3042-020 is a reliable, cost-effective choice for labs processing large batch volumes in pharmaceutical QC, bioanalytical, and LC-MS/MS sample preparation.
Technical Specifications
| Specification | Value |
|---|---|
| Part Number (MPN) | 208-3042-020 |
| Capacity | 2.4–3.5 mL |
| Column Style | Surety® Midi 1.9″ |
| Filter Pore Size | 15–45 microns (Fine Filter) |
| Material | Low-Density Polyethylene (LDPE) |
| Color | Natural |
| Sterility | Non-Sterile |
| Pack Size | 1000/Bag |
| BPA / Phthalate / Latex | BPA-Free, Phthalate-Free, Latex-Free |
| Country of Origin | USA |
Applications
- LC-MS/MS filtrate preparation: fine-filter pore size removes residual particulates from protein precipitation supernatants prior to injection, reducing analytical column fouling and carryover
- Confirmatory reference methods: GC-MS and LC-UV post-SPE cleanup requiring high-clarity eluate
- Pharmaceutical QC filtration: dissolution testing compatible with USP Apparatus I/II aqueous dissolution media
- Bioanalytical and PK studies: plasma and urine extract cleanup at higher sample volumes
- Manual pressure-assisted elution: the flexible LDPE body allows gentle finger compression to drive filtrate flow without a centrifuge or vacuum manifold
- Bench microcentrifuge workflows: compatible with 5 mL or 15 mL collection tubes at up to 3000×g
Compatibility
The Surety® Midi 1.9″ column fits standard tube-format SPE workflows and is compatible with vacuum manifold systems from Waters, Phenomenex, Supelco, and Agilent when used with appropriately sized tube adapters — verify adapter fit for your specific manifold configuration. For labs that prefer to avoid centrifuge or vacuum infrastructure entirely, the flexible LDPE body supports standalone manual pressure elution at the bench. These columns are also sized to accept 5 mL or 15 mL collection tubes for higher-volume sample loads. Laboratories needing a different working capacity can select from the broader Surety® line: the Mini 1.5″ format (1.5–2.4 mL, 500/Bag) and the Standard 2.3″ format (3.5–5.0 mL, 1000/Bag) round out the three-size range for size-matched method transfers.
Chemical Resistance
| Reagent / Condition | Compatibility |
|---|---|
| Aqueous buffers and saline | Excellent |
| Methanol | Good — suitable for standard SPE wash and elution protocols |
| Acetonitrile | Good — suitable for standard SPE wash and elution protocols |
| Dilute acids and bases (SPE modifiers) | Good — short-term contact at working concentrations |
| Concentrated aromatic or chlorinated solvents | Not recommended |
Quality & Procurement
Made in USA, these Surety® columns are produced from FDA-compliant LDPE resin that is BPA-free, phthalate-free, and latex-free, ensuring low extractables that are critical when downstream detection is by LC-MS/MS. Caplugs® Evergreen manufactures to consistent dimensional tolerances so filter integrity and fit are repeatable across every bag in a production lot. LabSupplies.com is an authorized dealer and ships from USA inventory, typically same business day for stocking items, with volume pricing available for institutional purchasers, core facilities, and contract research organizations processing large batches.
Frequently Asked Questions
Do these columns require a centrifuge or vacuum manifold?
No — the LDPE body is flexible enough to allow manual finger compression for pressure-assisted elution at the bench without any additional equipment. They are also compatible with benchtop centrifuges and tube-format vacuum manifolds if your workflow requires it.
What collection tube size is recommended for the Midi 1.9″ format?
The 2.4–3.5 mL working capacity is matched to 5 mL or 15 mL collection tubes for higher-sample-load SPE workflows. Confirm the tube adapter fit if using a vacuum manifold from a third-party supplier.
Are these columns suitable for LC-MS/MS sample preparation?
Yes. The 15–45 micron fine-filter pore size is specifically suited to removing residual particulates from protein precipitation filtrates prior to injection, and the low-extractable LDPE construction minimizes background interference in sensitive mass spectrometry detection.
Is the Surety® Midi 1.9″ available in other sizes for method transfers?
Yes. Caplugs® Evergreen offers the Surety® line in three formats to accommodate different sample volumes — the Mini 1.5″ (1.5–2.4 mL) and the Standard 2.3″ (3.5–5.0 mL) complement part number 208-3042-020 for size-matched workflows across a laboratory's full method portfolio.