1.5–2.4 mL Surety® Fine-Filter Mini Column, LDPE, Natural — SPE & LC-MS/MS Sample Prep (208-3040-020)
The Caplugs® Evergreen Surety® Mini 1.5″ column features a 15–45 micron fine-filter disk that delivers high-clarity filtrate for demanding sample-preparation workflows such as LC-MS/MS injection prep, SPE protein-precipitation cleanup, and confirmatory reference-method testing. Molded in Low-Density Polyethylene (LDPE) in a 1.5–2.4 mL working-capacity body, these columns fit standard 2 mL microcentrifuge collection vessels and ship non-sterile in convenient 500/Bag quantities. Made in USA, the Surety® line is engineered with low extractables and FDA-compliant, BPA-free resin — making it a reliable choice wherever sensitive downstream MS detection is involved.
Technical Specifications
| Specification | Value |
|---|---|
| Part Number (MPN) | 208-3040-020 |
| Product Type | Surety® Column, Fine Filter |
| Filter Pore Size | 15–45 microns |
| Style | Mini 1.5″ |
| Working Capacity | 1.5–2.4 mL |
| Material | Low-Density Polyethylene (LDPE) |
| Color | Natural |
| Sterility | Non-Sterile |
| Pack Size | 500/Bag |
| BPA / Phthalate / Latex | BPA-Free, Phthalate-Free, Latex-Free |
| Country of Origin | USA |
Applications
- LC-MS/MS injection preparation: The 15–45 micron fine filter removes residual particulates from protein-precipitation filtrates, protecting analytical columns and reducing costly column replacements.
- Solid-phase extraction (SPE) workflows: Compatible with bench microcentrifuge (up to 3,000 × g) and vacuum manifold platforms for efficient loading, washing, and elution steps.
- Confirmatory reference-method testing: High-clarity filtrate supports GC-MS and LC-UV confirmatory assays in clinical and forensic toxicology laboratories.
- Manual pressure-assisted elution: The inherent flexibility of LDPE allows gentle finger pressure to accelerate flow through the fine-filter disk without a centrifuge — a practical advantage during manual sample-prep runs.
- General sample cleanup: Dilute organic modifier and aqueous buffer clarification ahead of any chromatographic or immunoassay platform requiring low-particulate samples.
Compatibility
The Surety® Mini 1.5″ column body is sized to seat directly into standard 2 mL microcentrifuge collection tubes, making it compatible with bench centrifuge workflows at up to 3,000 × g. For higher-throughput labs, the column format is compatible with Waters®, Phenomenex®, and Supelco® 96-well and tube-format SPE vacuum manifolds — verify tube adapter dimensions before deployment. The LDPE flex body also supports standalone manual pressure-elution at the bench without any additional hardware. Laboratories evaluating larger capacity needs may consider the Surety® Midi 1.9″ (208-3042-020, 2.4–3.5 mL) or the Surety® Standard 2.3″ (208-3045-020, 3.5–5.0 mL) siblings in the same product line.
Chemical Resistance
| Reagent / Condition | Compatibility |
|---|---|
| Aqueous buffers and saline | Excellent |
| Dilute acids and bases | Excellent |
| Dilute organic modifiers (methanol, acetonitrile <50%) | Good — short-term contact |
| Alcohols (ethanol, isopropanol) | Good — short-term contact |
| Concentrated chlorinated solvents (chloroform, DCM) | Not recommended |
| Aromatic solvents (toluene, xylene) | Not recommended |
| Autoclaving | Not recommended (LDPE) |
Quality & Procurement
Made in USA, these Surety® columns are produced by Caplugs® Evergreen under ISO 9001 quality management from FDA-compliant LDPE resin that is BPA-free, phthalate-free, and latex-free. The fine-filter pore size of 15–45 microns provides tighter particulate exclusion than medium-filter alternatives, and LDPE's inherently low extractables profile makes it particularly well-suited for sensitive mass-spectrometric detection. LabSupplies.com is an authorized Caplugs® Evergreen dealer shipping from USA inventory; most stocking items ship the same business day, and volume pricing is available for institutional, hospital, and grant-funded procurement teams.
Frequently Asked Questions
What collection tube does this column fit?
The Mini 1.5″ body is designed to seat into a standard 2 mL microcentrifuge collection tube. Confirm your tube's inner-diameter spec if you are using a non-standard vessel or a manifold adapter.
Can I use these columns without a centrifuge?
Yes. Because the column body is molded from flexible LDPE, analysts can apply gentle finger pressure to assist flow through the fine-filter disk in manual, standalone bench workflows — no centrifuge is required for pressure-assisted elution.
How does the fine filter (15–45 microns) differ from a medium-filter column?
The tighter pore range of 15–45 microns provides greater particulate exclusion than a medium-filter option, yielding a higher-clarity filtrate. This translates directly to fewer analytical column fouling events and lower downstream column replacement costs in LC-MS/MS and confirmatory reference-method workflows.
Are these columns compatible with organic solvents used in SPE washes?
LDPE tolerates aqueous buffers, dilute acids and bases, and short-term contact with dilute organic modifiers such as methanol and acetonitrile commonly used in SPE wash and elution steps. Concentrated chlorinated or aromatic solvents are not recommended, as they can swell or permeate LDPE.