CryoSure® Cryogenic Vial Screw Caps — HDPE, Yellow, 200/Bag (300-3900-Y20)
These yellow High-Density Polyethylene screw caps are purpose-built for CryoSure® cryogenic vials, rated for liquid nitrogen vapor phase and immersion storage at -196°C as well as -80°C mechanical freezer archive. Supplied 200 per bag, part number 300-3900-Y20 suits biobank programs, clinical biorepositories, and cell biology labs that rely on color-coded specimen routing to manage large cryogenic inventories.
Technical Specifications
| Specification | Value |
|---|---|
| Part Number (MPN) | 300-3900-Y20 |
| Sub-brand | CryoSure® (Caplugs® Evergreen) |
| Material | High-Density Polyethylene (HDPE) |
| Color | Yellow |
| Cryogenic Rating | LN₂ vapor phase and immersion (-196°C) |
| Freezer Storage | -80°C mechanical freezer compatible |
| Autoclave Compatibility | 121°C / 15 psi |
| Pack Size | 200/Bag |
| BPA / Phthalates | BPA-free; phthalate-free |
| Country of Origin | USA (California) |
Applications
- Biobank cryogenic archive: capping CryoSure® vials for long-term LN₂ vapor phase and immersion storage at -196°C
- -80°C mechanical freezer biorepositories requiring verified HDPE cryo-stability
- Cell line preservation: archiving DMSO-protected cell lines in standard 5–10% cryoprotectant media
- Clinical specimen repositories using yellow color-designation for blood culture and ACD-preserved cryogenic specimens per CLSI H3 SPS/ACD convention
- Multi-specimen cryo box programs leveraging the 12-color CryoSure® cap range for color-coded specimen routing
Compatibility
These caps are designed specifically for CryoSure® cryogenic vials and are engineered to maintain thread integrity through the full range of cryogenic temperatures, from -80°C mechanical freezer storage down to -196°C LN₂ immersion. They are not interchangeable with standard HDPE tube caps, which are not rated for liquid nitrogen temperatures. For high-volume programs requiring the same yellow cap, the 1000-count bulk pack (300-3900-Y2K) offers the identical cap in larger quantity. The CryoSure® color system spans 12 colors, allowing labs to assign cap color to specimen type, collection protocol, or storage tier without relabeling individual vials.
Chemical Resistance
| Reagent / Condition | Compatibility |
|---|---|
| Liquid nitrogen (-196°C), vapor and immersion | Excellent — engineered for LN₂ service |
| -80°C mechanical freezer storage | Excellent — HDPE cryo-toughened |
| Autoclave (121°C / 15 psi) | Compatible |
| DMSO (5–10% cryoprotectant concentrations) | Good — standard cryo media concentrations |
| Aqueous cryoprotectants (FBS, glycerol, Bambanker) | Excellent |
| Aqueous buffers and saline | Excellent |
| Concentrated organic solvents | Not recommended |
Quality & Procurement
Made in USA at Caplugs® Evergreen's California manufacturing facility, these caps are precision-molded under ISO 9001 quality management from BPA-free, phthalate-free HDPE resin. LabSupplies.com is an authorized Caplugs® Evergreen dealer, shipping from USA inventory to reference laboratories, hospital systems, biotech companies, and federal procurement offices. Tiered institutional pricing is available for high-volume and grant-funded programs; the 1000-count yellow cap pack (300-3900-Y2K) is stocked for programs with recurring large-format needs.
Frequently Asked Questions
Are these caps rated for direct liquid nitrogen immersion, or vapor phase only?
They are rated for both LN₂ vapor phase and full LN₂ immersion storage at -196°C, as well as -80°C mechanical freezer archive.
Can these caps be autoclaved before use?
Yes — the HDPE construction is compatible with standard autoclave cycles at 121°C and 15 psi, supporting sterile workflow preparation.
What does the yellow color designation indicate?
Within the CryoSure® 12-color system, yellow corresponds to the CLSI H3 SPS/ACD convention, commonly used to designate blood culture and ACD-preserved cryogenic specimens. Labs may also adopt yellow for any internally defined specimen category using their own color-coding protocol.
Do these caps fit vials from other manufacturers?
These screw caps are designed for CryoSure® cryogenic vials. Compatibility with vials from other manufacturers depends on thread geometry and should be verified before use. Standard HDPE caps not rated for cryogenic service should never be substituted for LN₂ applications.