Caplugs® Evergreen
100–120 µL Microplates, Flat Bottom, PS, Natural — 222-8210-01I | 50/Box | Caplugs® Evergreen
100–120 µL Microplates, Flat Bottom, PS, Natural — 222-8210-01I | 50/Box | Caplugs® Evergreen
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Quick Reference
| Part Number | 222-8210-01I |
|---|---|
| Format | 384-well microplate with matching lid |
| Well Bottom | Flat |
| Well Volume | 0.112 mL (112 µL) per well |
| Material | Polystyrene (PS) |
| Color | Natural |
| Lid | Included — individually packed with plate |
| Pack Size | 50/Box Individually Packed |
| Sterility | Sterile |
| Primary Use | High-throughput screening, miniaturized ELISA, compound libraries |
| Origin | Made in USA |
| Price | $175.45/Box ($3.5090/plate) |
Technical Narrative
The Caplugs® Evergreen 222-8210-01I is a 384-Well Flat Bottom PS Sterile Microplate with Lid, 0.112 mL (112 µL) per well, individually packed, 50/Box. The 384-well format provides 4× the well density of the standard 96-well plate in the same SBS footprint — enabling higher throughput screening and sample processing at proportionally lower reagent and sample volume per well. The 112 µL well volume is suited to miniaturized ELISA, high-throughput compound screening, cell-based assays at reduced scale, and kinetic plate-reader assays.
PS flat-bottom, surface-treated for adherent cell culture and ELISA coating. Plate reader compatible across 400–750 nm. Each plate individually packed with matching lid. BPA-free, phthalate-free, FDA-compliant,
Procurement economics: $175.45/Box (50 plates), $3.5090/plate. Sibling: 222-8030-01F (96-Well Flat Bottom 0.37 mL IP 100/Box). LabSupplies.com ships from USA inventory, typically same business day.
Technical Specifications
| Part Number | |
|---|---|
| Caplugs Item # | |
| Format | 384-well microplate with matching lid |
| Well Bottom | Flat |
| Well Volume | 0.112 mL (112 µL) per well |
| Material | Polystyrene (PS) |
| Color | Natural |
| Lid | Included — individually packed |
| Sterility | Sterile |
| Pack Size | 50/Box Individually Packed |
| Application | High-throughput screening, miniaturized ELISA, compound libraries |
| BPA / Phthalate | BPA-Free, Phthalate-Free, Latex-Free |
| Country of Origin | USA |
| Price | $175.45/Box ($3.5090/plate) |
384-Well Flat Bottom Microplate Applications
The is the high-density format for miniaturized assays. Requires 384-channel or 16-channel multichannel pipettes for efficient dispensing.
| Application | Setting / Configuration | Notes |
|---|---|---|
| High-throughput screening (HTS) | Compound library screening, 384-well | 4× throughput vs 96-well at same plate footprint |
| Miniaturized ELISA | 384-well flat, 100 µL/well assay | Reduce antibody and antigen consumption vs 96-well |
| Kinetic enzyme assays | Plate reader, 384-well format | PS flat: compatible with 384-well plate reader mode |
| DNA / RNA quantification | PicoGreen, RiboGreen, NanoDrop-plate mode | 384-well for high-throughput nucleic acid QC |
| Cell-based HTS assay | 384-well cell seeding, compound dosing | Miniaturized cell viability or reporter assay |
| Compound dilution library | Automated liquid handler, 384-well | 384 × 8× more compounds vs 96-well per run |
| PCR product staging | Post-PCR product in 384-well for sequencing | Miniaturized format for sequencing plate submission |
Chemical Resistance — Polystyrene (PS) — 384-Well Microplate
Compatibility reference at typical laboratory conditions.
| Reagent / Condition | Compatibility | Notes |
|---|---|---|
| Aqueous buffers / saline | Excellent | PS flat-bottom: compatible across pH 4–10. |
| Cell culture media | Excellent | PS: standard cell culture material. |
| Formalin (10%) | Excellent | Compatible for miniaturized cell fixation. |
| Methanol (<100%) | Limited | Short-term compatible; avoid prolonged contact. |
| DMSO (<1%) | Good | Compatible at standard compound screening concentrations. |
| Detergents (Tween-20) | Good | Compatible at standard ELISA wash concentrations. |
| UV (<320 nm) | Not Transparent | PS opaque to UV; not for UV-absorbance methods. |
| Acetone / chloroform | Not Compatible | Dissolves PS; do not use. |
Clinical & Research Laboratory Applications
Caplugs® Evergreen 384-well flat-bottom PS sterile microplates serve pharmaceutical high-throughput screening, genomics, and clinical diagnostics laboratories requiring the high-density plate format. In drug discovery, the 384-well plate is the standard format for primary HTS compound library screening — each plate tests 384 compounds (or 352 with control wells) at a fraction of the reagent and compound cost of 96-well primary screening. Genomics laboratories use 384-well plates for PCR setup with automated liquid handlers, NGS library prep, and DNA quantification assays where the 4× throughput per plate reduces run time and consumable cost. Miniaturized ELISA in 384-well format reduces primary and secondary antibody consumption by ~75% vs 96-well while maintaining signal-to-noise with 100–120 µL well volumes.
U.S. Manufacturing, Quality & Institutional Procurement
Caplugs® Evergreen products are manufactured in the United States under ISO 9001 quality management from FDA-compliant, food-contact-grade resins. BPA-free, phthalate-free, and latex-free, with material-disclosure documentation supporting CAP, CLIA, and ISO 15189 laboratory accreditation audits.
LabSupplies.com is an authorized dealer for the full Caplugs Evergreen catalog and ships directly from USA inventory — typically same business day for stocking SKUs. We offer below retail pricing on volume orders, tiered institutional and academic pricing, and direct support for grant-funded laboratories and government procurement channels. Lab managers and procurement officers can request a written quote or speak with a product specialist directly from our sales engineering team.
Frequently Asked Questions
Are the 384-well plates sterile?
Yes. Sterile — each plate individually packed with lid, 50/Box.
What pipetting equipment is needed for 384-well plate use?
384-well plates require specialized liquid handling for efficient use: 16-channel multichannel pipette (spans 2 rows of a 96-well plate = one row of 384-well plate, requires repositioning), 384-channel pipette (fills entire plate in one step), or robotic liquid handler with 384-well head. Manual pipetting of individual wells is feasible but slow — 384-well plates are most efficient with multichannel or automated liquid handling.
Is the 384-well plate compatible with standard 96-well plate readers?
Yes for readers with 384-well mode. Most modern plate readers (SpectraMax, Synergy, CLARIOstar, Varioskan, etc.) support 384-well SBS-format plates. Verify your reader's supported well formats and confirm the 384-well reading mode is enabled. The SBS footprint is identical to 96-well.
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