Caplugs® Evergreen
0.112 mL Microplates, Flat Bottom, PPC, Natural — 290-8388-08F | 10/Box | Caplugs® Evergreen
0.112 mL Microplates, Flat Bottom, PPC, Natural — 290-8388-08F | 10/Box | Caplugs® Evergreen
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384-Well Flat Bottom Microplates, 0.112 mL Well Volume, PPC, Natural — 290-8388-08F | 10/Box (100/Case)
| Quick Reference — 290-8388-08F | |
|---|---|
| Well Format | 384-well SBS/ANSI |
| Bottom | Flat Bottom |
| Well Volume | 0.112 mL |
| Material | Polypropylene Copolymer (PPC) |
| Color | Natural |
| DMSO Compat. | ✓ Superior to PP and PS — all concentrations |
| Cryo Storage | ✓ -80°C compatible |
| Autoclave | ✓ Compatible |
| vs PS/PP 384 | PPC: DMSO + -80°C cryo + autoclave (PS and PP cannot match all three) |
| Pack Size | 10/Box (100/Case) |
| Price | $273.21 / Box ($2.7321 / plate) |
Technical Narrative
The Caplugs® Evergreen is a 384-well flat-bottom Polypropylene Copolymer (PPC) microplate — the highest-performance material specification in the Caplugs® Evergreen 384-well range for compound library management programs requiring the combination of full DMSO compatibility, -80°C cryogenic archive stability, and autoclave sterilization capability that neither PS nor standard PP can deliver simultaneously. PPC's copolymer matrix provides superior resistance to DMSO at all concentrations versus standard PP, enhanced dimensional stability at -80°C ultra-low temperature versus standard PP (which can become brittle at sustained -80°C), and autoclave compatibility at 121°C for sterile compound plate supply.
At 384-well format density — 384 compound positions per plate, 0.112 mL per well — the material specification matters more than at 96-well scale: a single 384-well compound archive plate may represent 384 unique compound stocks, and material failure (cracking, DMSO vapor loss, dimensional drift in acoustic dispensing) represents the loss of irreplaceable compound information. PPC's enhanced copolymer toughness versus standard PP provides the dimensional stability and crack resistance required for long-term 384-well compound library archiving at -80°C and repeated acoustic dispensing cycles at ambient temperature from the same plate.
At $273.21 per Box of 10 — $2.7321 per plate — the PPC 384-well carries a significant premium over PS 384-well (290-8217-010, $182.92/box) that is specifically justified for compound library programs where DMSO tolerance, -80°C cryo archiving, and autoclave sterilization are simultaneous requirements. For standard ELISA and fluorescence HTS, PS 384-well is the cost-effective choice.
Technical Specifications — Caplugs® Evergreen
| Specification | Value |
|---|---|
| Part Number | |
| Caplugs Item # | 290838808FE1 |
| Well Format | 384-well SBS/ANSI |
| Bottom | Flat Bottom |
| Well Volume | 0.112 mL |
| Material | Polypropylene Copolymer (PPC) |
| Color | Natural |
| DMSO Compat. | ✓ Excellent — superior to PS and PP |
| Cryo Storage | ✓ -80°C ultra-low temperature compatible |
| Autoclave | ✓ Compatible (121°C / 15 psi) |
| vs PS 384 | 290-8217-010 (PS): aqueous HTS/ELISA; this PPC: DMSO + cryo + autoclave |
| Pack Size | 10/Box (100/Case) |
| BPA/Phthalate | BPA-free; no phthalate plasticizers |
| Country of Origin | Made in U.S.A. (California) |
PPC 384-Well Workflow Compatibility — Maximum Chemical & Cryo Resistance
PPC provides the highest chemical and temperature resistance of any standard 384-well microplate material:
| Application | Assay / Use | Notes |
|---|---|---|
| DMSO compound library (384-well) | High-DMSO compound stock plates at 384-well scale | PPC resists DMSO where standard PS and PP can degrade at high conc. |
| Acoustic dispensing source | 384-well PPC source plate for Echo/Mosquito | PPC superior to PP for repeated acoustic dispensing DMSO cycles |
| High-concentration compound store | >50% DMSO compound stocks at 384-well density | PPC maintains dimensional stability under prolonged DMSO exposure |
| Low-temperature storage (384) | 384-well compound archive at -80°C | PPC cold-temperature stability at -80°C ultra-low temp |
| 384-well PP alternative | When PS or PP 384-well fails under DMSO or cold | PPC: superior DMSO + cryo performance vs PS and standard PP |
| Automated library management | 384-well compound library management systems | PPC dimensional stability in high-throughput automated plate handlers |
| Combinatorial chemistry storage | Compound intermediate and product storage at 384 | PPC inertness to diverse organic compounds and solvents |
| Pharmacokinetics sample storage | PK plasma sample plates at 384-well density | PPC suitable for protein-containing matrix with organic solvent |
PPC is the premium 384-well material — specify when DMSO compound storage, acoustic dispensing cycling, -80°C archiving, or autoclave sterilization are required. For standard aqueous 384-well HTS and ELISA, PS (290-8217-010) provides equivalent performance at lower cost.
Chemical Resistance — Polypropylene Copolymer (PPC)
PPC provides the broadest chemical resistance of standard 384-well plate materials — superior to PS and standard PP for DMSO, cryogenic storage, and repeated organic solvent exposure.
| Reagent / Condition | Compatibility |
|---|---|
| DMSO (all concentrations) | ✓ Excellent — superior to PP and PS |
| Aqueous buffers / media | ✓ Excellent |
| Short-chain alcohols | ✓ Excellent |
| Concentrated organic solvents | ✓ Good — broader than PP |
| Dilute acids / alkalies | ✓ Excellent |
| Storage at -80°C | ✓ Suitable — PPC cryo stability |
| Autoclave (121°C / 15 psi) | ✓ Compatible |
| Chlorinated solvents (brief) | ✓ Good |
Laboratory Applications
The serves pharmaceutical compound library management programs archiving 384-well DMSO compound stocks at -80°C; acoustic dispensing programs (Echo, Mosquito) cycling 384-well PPC source plates for high-DMSO compound dispensing; drug discovery programs requiring sterile 384-well compound plates via autoclave; combinatorial chemistry programs storing diverse organic compound intermediates; and any 384-well program where PS and standard PP chemical performance is insufficient.
U.S. Manufacturing, Quality & Institutional Procurement
Every Caplugs® Evergreen lot is precision-molded at our California manufacturing facility and subject to rigorous dimensional inspection and material purity verification. We supply reference laboratories, hospital systems, biotech firms, and federal procurement offices under institutional pricing programs with blanket-order support and same-day shipping on stocked inventory. Request a sample below to validate before committing to volume.
Frequently Asked Questions — Caplugs® Evergreen
What makes PPC 384-well different from PS (290-8217-010) and PP 384-well?
PPC (Polypropylene Copolymer) provides three simultaneous advantages over both PS and standard PP at 384-well scale: (1) DMSO tolerance superior to both — PPC resists DMSO-induced degradation better than standard PP for prolonged DMSO compound storage; (2) -80°C cryo stability — PPC maintains toughness at ultra-low temperature where standard PP can become brittle and crack; (3) Autoclave compatibility — identical to PP, not available in PS. PS (290-8217-010) is the cost-effective choice for standard ELISA and HTS. PPC is specified when all three — DMSO, cryo, autoclave — are required.
Is PPC 384-well suitable for -80°C compound library archiving?
Yes. PPC (Polypropylene Copolymer) maintains structural integrity and dimensional stability at -80°C ultra-low temperature — the critical requirement for 384-well compound library archive plates that cycle between -80°C storage and ambient temperature dispensing. Standard PP can develop brittleness and micro-cracking under repeated -80°C freeze-thaw cycling. PPC's copolymer rubber-toughened matrix resists this brittleness pathway — making it the preferred material for high-value 384-well compound archive plates.
Is the PPC plate compatible with acoustic dispensers (Echo, Mosquito)?
Yes. PPC 384-well plates are compatible with acoustic liquid dispensers in SBS-standard 384-well footprint. PPC's superior DMSO resistance and dimensional stability make it the preferred material for 384-well acoustic dispensing source plates cycling repeatedly between -80°C storage and ambient temperature dispensing. Confirm your dispenser's source plate specification against PPC plate dimensions.
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