0.35 mL Microplates, Flat Bottom, PS, Natural — 290-8118-01C | 10/Box | Caplugs® Evergreen

96-Well Chamfered Bottom Microplates, 0.35 mL Well Volume, PS, Natural — 290-8118-01C | 10/Box (100/Case)

Technical Narrative

The Caplugs® Evergreen is a 96-well chamfered-bottom Polystyrene (PS) microplate — a geometry refinement over standard flat-bottom wells that provides measurable workflow improvements in automated liquid handling environments. The chamfer — a beveled taper in the upper portion of each well wall — guides pipette tip and needle alignment during high-speed robotic dispensing and aspiration, reducing the tip-crash events and well-wall contact that occur when dispensing heads are operating at maximum speed with positional tolerances at the edges of SBS specification. The flat well floor is retained for absorbance reads — chamfered geometry affects only the upper well, preserving consistent path length for quantitative assay measurements.

The chamfered well geometry also reduces the well edge effect — the phenomenon where edge wells in standard flat-bottom plates exhibit higher evaporation rates and temperature gradients versus interior wells during extended cell culture and incubation. The chamfer modifies the meniscus geometry and surface area at the well top, reducing differential evaporation between edge and center wells in high-throughput screening programs running 24–72 hour incubation plates. This is a material consideration for IC50 and EC50 dose-response screens where edge-well concentration drift over long incubations introduces systematic assay artifacts.

At $143.72 per Box of 10 — $1.4372 per plate — the delivers chamfered geometry optimization at a per-plate cost premium justified by reduced tip crash rate, improved dispense accuracy, and reduced edge effect in automated HTS workflows.

Technical Specifications — Caplugs® Evergreen

Automation & Assay Compatibility — Chamfered Bottom

The chamfered well geometry of the provides specific workflow advantages in automation-intensive environments:

Chamfered bottom retains flat well floor for absorbance reads — path length is consistent at the flat base. The chamfer only modifies the upper well wall geometry for needle guidance and edge-effect reduction.

Chemical Resistance — Polystyrene (PS)

PS provides excellent resistance to aqueous assay reagents. Not autoclave-compatible.

Laboratory Applications

The serves pharmaceutical HTS programs running automated compound screening on robotic liquid handling platforms; contract research organizations running multi-plate ELISA batches with automated washers and dispensers; cell-based assay programs requiring reduced edge-effect variation across 96-well plates; acoustic dispensing programs where chamfered geometry improves droplet ejection accuracy; and any laboratory running automation at the performance limits of standard flat-bottom SBS plates.

U.S. Manufacturing, Quality & Institutional Procurement

Every Caplugs® Evergreen lot is precision-molded at our California manufacturing facility and subject to rigorous dimensional inspection and material purity verification. We supply reference laboratories, hospital systems, biotech firms, and federal procurement offices under institutional pricing programs with blanket-order support and same-day shipping on stocked inventory. Request a sample below to validate before committing to volume.

Frequently Asked Questions — Caplugs® Evergreen

What does 'chamfered bottom' mean and how does it differ from standard flat bottom?

A chamfered well has a flat bottom (for consistent absorbance path length) with beveled — angled — transitions in the upper wall of the well. Standard flat-bottom wells have vertical walls from top to bottom. The chamfer guides pipette tips and robotic needle arrays toward the well center during high-speed automated dispensing, reducing tip-wall contact that causes carryover, well damage, and dispense volume error. The flat floor is identical to standard flat-bottom plates for absorbance-based ELISA and colorimetric reads.

Does the chamfered geometry affect absorbance reads?

No. The chamfer is in the upper portion of the well wall only — the well floor remains flat, maintaining consistent path length across the well volume for absorbance reads at 405, 450, 490, 570, and 630 nm. All standard plate reader detection modes (absorbance, fluorescence, luminescence) are compatible with chamfered well geometry.

Is the chamfered plate compatible with standard automated plate handlers?

Yes. The conforms to SBS/ANSI 96-well standard footprint dimensions and is compatible with all standard robotic liquid handlers (Hamilton STARlet/STAR, Tecan Freedom EVO/Fluent, Agilent Bravo), plate washers, and plate readers. The chamfered geometry specifically improves performance at the high-speed end of dispense head travel where standard flat-wall plates experience the most tip-contact events.