Caplugs® Evergreen
Tissue Embedding Rings, PS, Yellow — 258-4014-Y10 | 500/Bag | Caplugs® Evergreen
Tissue Embedding Rings, PS, Yellow — 258-4014-Y10 | 500/Bag | Caplugs® Evergreen
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Tissue Embedding Rings, High Impact Polystyrene (HIPS), Yellow — 258-4014-Y10 | 500/Bag
| Quick Reference — 258-4014-Y10 | |
|---|---|
| Product | Tissue Embedding Ring |
| Material | High Impact Polystyrene (HIPS) |
| Color | Yellow |
| Paraffin Compat. | ✓ Compatible (56–65°C) |
| Xylene Compat. | ✓ Compatible |
| Formalin Compat. | ✓ Compatible |
| Sterility | Non-Sterile |
| Pack Size | 500 / Bag |
| Price | $57.89 / Bag ($0.1158 / ring) |
Technical Narrative
The Caplugs® Evergreen is a yellow High Impact Polystyrene (HIPS) tissue embedding ring — the consumable that holds the tissue cassette base in correct orientation within the embedding mold during paraffin infiltration at standard histology embedding center temperatures (56–65°C). The ring's precise dimensional fit with standard histology cassette bases ensures consistent tissue orientation and paraffin block face geometry — directly affecting section quality, ribbon continuity, and the number of diagnostic-quality levels obtainable per block. Yellow rings provide high-visibility contrast under both fluorescent and LED grossing bench lighting, and are used for priority or STAT specimen designation in pathology workflows requiring rapid turnaround identification.
High Impact Polystyrene (HIPS) is specified over standard PS for tissue embedding rings because its rubber-toughened matrix withstands the thermal cycling, xylene exposure, and mechanical handling forces of histology tissue processing without the brittleness or cracking that limits standard PS at embedding temperatures. HIPS is compatible with the full histology solvent sequence — paraffin wax, xylene and xylene substitutes (HistoClear, Sub-X), all ethanol concentrations, IPA, and 10% NBF formalin — ensuring the ring maintains structural integrity throughout cassette processing, embedding, and block trimming workflows. The yellow pigmentation is compounded into the HIPS matrix — not a surface coating — ensuring permanent color retention through solvent exposure.
At $57.89 per 500/Bag — $0.1158 per ring — the delivers high-throughput histopathology consumable economics for surgical pathology cores processing hundreds of blocks per shift. The complete Caplugs® Evergreen tissue embedding ring color range: 258-4010-W10 (White, $57.89/Bag); 258-4011-P10 (Pink, $57.89/Bag); 258-4012-B10 (Blue, $57.89/Bag); 258-4013-G10 (Green, $57.89/Bag) — enabling full color-scheme procurement from a single vendor for multi-category color-coded embedding programs.
Technical Specifications — Caplugs® Evergreen
| Specification | Value |
|---|---|
| Part Number | |
| Caplugs Item # | 2584014Y10E1 |
| Product Type | Tissue Embedding Ring |
| Material | High Impact Polystyrene (HIPS) |
| Color | Yellow |
| Paraffin Compat. | ✓ Compatible at standard embedding temperatures (56–65°C) |
| Xylene Compat. | ✓ Compatible |
| Formalin Compat. | ✓ Compatible (10% NBF) |
| Sterility | Non-Sterile |
| Pack Size | 500 / Bag |
| Reorder Unit | Bag of 500 |
| Application | Histopathology tissue embedding, surgical biopsy, frozen section |
| BPA / Phthalate | BPA-free; no phthalate plasticizers |
| Country of Origin | Made in U.S.A. (California) |
Histopathology Workflow Compatibility —
The yellow HIPS tissue embedding ring is compatible with standard paraffin embedding workflows across the following specimen types and applications:
| Application | Specimen Types | Notes |
|---|---|---|
| Surgical biopsy embedding | Prostate needle core, cervical biopsy, skin punch | Ring holds cassette-base position during paraffin infiltration |
| Endoscopic biopsy | GI mucosal biopsy, esophageal, gastric specimens | Small ring format accommodates endoscopic biopsy cassette sizes |
| Excisional specimen embedding | Breast lumpectomy, melanoma excision, lymph node | Ring maintains orientation during embedding at wax station |
| Needle core and TRUS biopsy | Prostate, liver, kidney, thyroid needle cores | Color coding enables laterality and site designation per core |
| Frozen section support | Intraoperative margin and sentinel node | Ring used in fresh tissue embedding for cryostat sectioning |
| Research tissue microarray (TMA) | Multi-core donor block embedding | Precision ring positioning enables consistent core depth for TMA |
| Cytology cell block | Cell pellet, peritoneal fluid, BAL | Ring contains paraffin cell block during embedding |
| Veterinary histopathology | Animal tissue biopsy, necropsy specimens | Same embedding ring format as human histopathology |
Tissue embedding rings are designed for use with standard histology cassettes and embedding centers (Leica EG1150, Thermo Shandon Histocentre, Sakura Tissue-Tek). Confirm ring-to-cassette fit with a sample before bulk purchase if using non-standard cassette formats.
Chemical & Processing Compatibility — High Impact Polystyrene (HIPS)
The is molded from High Impact Polystyrene (HIPS) — selected over standard PS for its enhanced toughness and resistance to the solvents used in histology tissue processing. HIPS withstands the full histology processing solvent sequence without warping or cracking.
| Reagent / Condition | HIPS Compatibility |
|---|---|
| Paraffin wax (56–65°C) | ✓ Compatible — primary embedding medium |
| Xylene / xylene substitute | ✓ Compatible — standard tissue processing solvent |
| Ethanol (all concentrations) | ✓ Compatible — tissue dehydration series |
| Isopropanol (IPA) | ✓ Compatible |
| Formalin (10% buffered) | ✓ Compatible — standard tissue fixative |
| Hematoxylin / eosin staining | ✓ Compatible — ring does not contact staining baths |
| Acetone (brief contact) | ✓ Good — brief incidental contact |
| Concentrated organic solvents | ✓ Good — HIPS has better solvent resistance than standard PS |
| Autoclave (121°C / 15 psi) | ✗ Not recommended — HIPS softens at embedding wax temps |
HIPS is rated for standard histology embedding center operating temperatures (56–65°C). Do not expose to temperatures above 75°C. Not autoclave-compatible.
Anatomic Pathology Laboratory Applications
The yellow tissue embedding ring serves hospital and reference anatomic pathology laboratories for surgical biopsy, excisional specimen, and resection block embedding; gastrointestinal and endoscopy pathology programs for mucosal biopsy embedding; genitourinary pathology for prostate needle core, bladder, and kidney biopsy processing; dermatopathology for punch and shave biopsy embedding; breast pathology for core needle and excisional specimen blocks; neuropathology and research histology for CNS tissue processing; veterinary diagnostic laboratories; and any pathology setting using color-coded embedding rings to designate specimen type, anatomic site, laterality, or processing priority. The 500/Bag format suits high-volume surgical pathology cores.
U.S. Manufacturing, Quality & Institutional Procurement
Every Caplugs® Evergreen lot is precision-molded at our California manufacturing facility and subject to rigorous dimensional inspection and material purity verification. We supply reference laboratories, hospital systems, and federal procurement offices under institutional pricing programs with blanket-order support and same-day shipping on stocked inventory. Request a compatibility sample below to validate fit with your cassette format before committing to volume.
Frequently Asked Questions — Caplugs® Evergreen
What histology cassette formats are compatible with the embedding ring?
The is designed for standard histology tissue cassettes used on Leica EG1150, Thermo Shandon Histocentre, and Sakura Tissue-Tek embedding centers. Always confirm ring-to-cassette fit with a sample set before large-volume purchase — cassette base dimensions vary slightly between manufacturers and can affect ring seating depth and paraffin block face geometry.
Why use HIPS rather than standard PS for tissue embedding rings?
High Impact Polystyrene (HIPS) is a rubber-toughened grade of PS that provides significantly better impact resistance and solvent toughness than standard PS at histology processing temperatures. Standard PS can become brittle and crack during xylene and ethanol exposure at embedding center temperatures (56–65°C). HIPS maintains structural integrity across the full histology solvent and temperature cycle — paraffin wax, xylene, all ethanol concentrations, and NBF formalin — without warping or releasing fragments into the embedding mold that could contaminate the paraffin block.
Is the yellow color permanent through xylene and paraffin processing?
Yes. The yellow pigmentation in the is compounded directly into the HIPS polymer matrix — not applied as a surface coating or dye. This means the color is stable through xylene, ethanol, formalin, and paraffin wax exposure without leaching, fading, or contaminating the embedding medium. Color stability through the full processing cycle is essential for reliable color-coded specimen identification at the embedding station.
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