{"product_id":"cryosure-cryogenic-round-vials-0-4ml-ppc-2203925080e1","title":"0.4 mL Vial Racks, Round Bottom, PPC, Natural — 220-3925-080 | 1000\/Bag | Caplugs® Evergreen","description":"\u003ch2\u003e0.4 mL CryoSure® Round-Bottom Cryogenic Vials — PPC, Natural, 1000\/Bag (220-3925-080)\u003c\/h2\u003e\n\u003cp\u003eThese 0.4 mL CryoSure® round-bottom cryogenic vials from Caplugs® Evergreen are constructed from polypropylene copolymer (PPC), a material engineered to remain flexible and crack-resistant across the full cryogenic temperature range — from –80°C ultra-low temperature (ULT) freezers through liquid nitrogen (LN₂) storage at –196°C. Supplied non-sterile in 1000\/Bag bulk packaging, part number 220-3925-080 is well suited for biobanking, cell line preservation, and clinical biospecimen archiving where consistent microvolume recovery is essential. The round bottom concentrates sample at the lowest point of the vial, enabling thorough recovery of small aliquots after thaw.\u003c\/p\u003e\n\n\u003ch2\u003eTechnical Specifications\u003c\/h2\u003e\n\u003ctable\u003e\n\u003cthead\u003e\u003ctr\u003e\n\u003cth\u003eSpecification\u003c\/th\u003e\n\u003cth\u003eValue\u003c\/th\u003e\n\u003c\/tr\u003e\u003c\/thead\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd\u003ePart Number (MPN)\u003c\/td\u003e\n\u003ctd\u003e220-3925-080\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eVolume\u003c\/td\u003e\n\u003ctd\u003e0.4 mL\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eVial Type\u003c\/td\u003e\n\u003ctd\u003eCryoSure® Cryogenic Round Vial\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eBottom Style\u003c\/td\u003e\n\u003ctd\u003eRound Bottom\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eCap Style\u003c\/td\u003e\n\u003ctd\u003eSnap Cap\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eCryogenic Rating\u003c\/td\u003e\n\u003ctd\u003eLN₂ \/ Vapor-Phase N₂ \/ –80°C ULT\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eMaterial\u003c\/td\u003e\n\u003ctd\u003ePolypropylene Copolymer (PPC)\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eColor\u003c\/td\u003e\n\u003ctd\u003eNatural\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eSterility\u003c\/td\u003e\n\u003ctd\u003eNon-Sterile\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003ePack Size\u003c\/td\u003e\n\u003ctd\u003e1000\/Bag\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eBPA \/ Phthalate Free\u003c\/td\u003e\n\u003ctd\u003eYes\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eCountry of Origin\u003c\/td\u003e\n\u003ctd\u003eUSA\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\n\u003ch2\u003eApplications\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003eBiobanking and long-term biological sample archiving in LN₂ or vapor-phase nitrogen dewars\u003c\/li\u003e\n\u003cli\u003eCell line and primary cell cryopreservation at –80°C ULT or below\u003c\/li\u003e\n\u003cli\u003eDNA and RNA aliquot storage where microvolume recovery and sample integrity are critical\u003c\/li\u003e\n\u003cli\u003eSerum and plasma aliquot cryopreservation for clinical and translational research workflows\u003c\/li\u003e\n\u003cli\u003eTissue sample archiving for CAP-, CLIA-, and ISO 15189-regulated clinical laboratories\u003c\/li\u003e\n\u003cli\u003eDry ice shipment of cryogenic biospecimens requiring vials rated for extreme cold\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003ch2\u003eChemical Resistance\u003c\/h2\u003e\n\u003ctable\u003e\n\u003cthead\u003e\u003ctr\u003e\n\u003cth\u003eReagent \/ Condition\u003c\/th\u003e\n\u003cth\u003eCompatibility\u003c\/th\u003e\n\u003c\/tr\u003e\u003c\/thead\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd\u003eAqueous buffers \/ saline\u003c\/td\u003e\n\u003ctd\u003eExcellent\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eDilute acids\u003c\/td\u003e\n\u003ctd\u003eExcellent\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eDilute bases\u003c\/td\u003e\n\u003ctd\u003eExcellent\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eMethanol\u003c\/td\u003e\n\u003ctd\u003eCompatible\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eIsopropanol (IPA)\u003c\/td\u003e\n\u003ctd\u003eCompatible\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eAcetonitrile\u003c\/td\u003e\n\u003ctd\u003eCompatible\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eAromatic \/ chlorinated solvents\u003c\/td\u003e\n\u003ctd\u003eLimited — verify before use\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\n\u003ch2\u003eQuality \u0026amp; Procurement\u003c\/h2\u003e\n\u003cp\u003eMade in USA, these CryoSure® vials are produced at Caplugs® Evergreen ISO-certified facilities using virgin-grade PPC resin that is BPA-free and phthalate-free. Lot-level quality controls ensure consistent vial geometry, wall thickness, and snap-cap seal integrity across every vial in the bag — providing the traceability documentation required by CAP, CLIA, and ISO 15189 accredited laboratories. LabSupplies.com is an authorized Caplugs® Evergreen dealer shipping from USA inventory, with tiered pricing available for high-volume institutional and grant-funded accounts.\u003c\/p\u003e\n\n\u003ch2\u003eFrequently Asked Questions\u003c\/h2\u003e\n\u003cp\u003e\u003cstrong\u003eAre these vials sterile?\u003c\/strong\u003e\u003cbr\u003eNo — the 0.4 mL CryoSure® vials are supplied non-sterile. For applications requiring sterile consumables, consider a DNase\/RNase-decontamination step or inquire about sterile configurations before ordering.\u003c\/p\u003e\n\n\u003cp\u003e\u003cstrong\u003eWhy use PPC instead of standard polypropylene for cryogenic storage?\u003c\/strong\u003e\u003cbr\u003eStandard PP homopolymer becomes brittle below approximately –40°C and can crack under thermal stress during freeze-thaw cycling. Polypropylene copolymer (PPC) retains flexibility and impact resistance down to –196°C, making it the preferred material for LN₂ and vapor-phase nitrogen applications.\u003c\/p\u003e\n\n\u003cp\u003e\u003cstrong\u003eWhat is the advantage of a round-bottom design at 0.4 mL?\u003c\/strong\u003e\u003cbr\u003eAt microvolumes, a round bottom concentrates the sample at the lowest point of the vial, minimizing dead volume and allowing more complete recovery after thawing — particularly important when working with precious or limited biospecimens.\u003c\/p\u003e\n\n\u003cp\u003e\u003cstrong\u003eDoes each bag include lot traceability information?\u003c\/strong\u003e\u003cbr\u003eYes. Every 1000\/Bag shipment includes lot number and manufacturing date documentation to support the chain-of-custody and traceability requirements of CAP-, CLIA-, and ISO 15189-accredited laboratories.\u003c\/p\u003e\n\n\u003cscript type=\"application\/ld+json\"\u003e{\"@context\":\"https:\/\/schema.org\/\",\"@type\":\"Product\",\"name\":\"0.4 mL CryoSure® Round-Bottom Cryogenic Vials, PPC, Natural, 1000\/Bag — Caplugs® Evergreen 220-3925-080\",\"sku\":\"2203925080E1\",\"mpn\":\"220-3925-080\",\"brand\":{\"@type\":\"Brand\",\"name\":\"Caplugs® Evergreen\"},\"material\":\"Polypropylene Copolymer (PPC)\",\"color\":\"Natural\",\"offers\":{\"@type\":\"Offer\",\"priceCurrency\":\"USD\",\"price\":\"85.09\",\"availability\":\"https:\/\/schema.org\/InStock\"}}\u003c\/script\u003e\n\u003cscript type=\"application\/ld+json\"\u003e{\"@context\":\"https:\/\/schema.org\/\",\"@type\":\"FAQPage\",\"mainEntity\":[{\"@type\":\"Question\",\"name\":\"Are these vials sterile?\",\"acceptedAnswer\":{\"@type\":\"Answer\",\"text\":\"No — the 0.4 mL CryoSure® vials are supplied non-sterile. 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