{"product_id":"caplugs-290-8218-01l-384-well-microplate-lid-ps-natural","title":"8218–01 L Microplates, PP, Natural — 290-8218-01L | 15\/Box | Caplugs® Evergreen","description":"\u003ch2\u003e384-Well Microplate Lids, Polystyrene (PS), Natural — 290-8218-01L | 15\/Box (105\/Case)\u003c\/h2\u003e \u003ctable\u003e \u003cthead\u003e\u003ctr\u003e\u003cth colspan=\"2\"\u003eQuick Reference — 290-8218-01L\u003c\/th\u003e\u003c\/tr\u003e\u003c\/thead\u003e \u003ctbody\u003e \u003ctr\u003e \u003ctd\u003e\u003cstrong\u003eWells\u003c\/strong\u003e\u003c\/td\u003e \u003ctd\u003e384-well SBS format\u003c\/td\u003e \u003c\/tr\u003e \u003ctr\u003e \u003ctd\u003e\u003cstrong\u003eMaterial\u003c\/strong\u003e\u003c\/td\u003e \u003ctd\u003ePolystyrene (PS)\u003c\/td\u003e \u003c\/tr\u003e \u003ctr\u003e \u003ctd\u003e\u003cstrong\u003eColor\u003c\/strong\u003e\u003c\/td\u003e \u003ctd\u003eNatural (transparent)\u003c\/td\u003e \u003c\/tr\u003e \u003ctr\u003e \u003ctd\u003e\u003cstrong\u003eDMSO Compat.\u003c\/strong\u003e\u003c\/td\u003e \u003ctd\u003e✓ Good ≤10% (PS)\u003c\/td\u003e \u003c\/tr\u003e \u003ctr\u003e \u003ctd\u003e\u003cstrong\u003eAutoclave\u003c\/strong\u003e\u003c\/td\u003e \u003ctd\u003e✓ Compatible (limited cycles)\u003c\/td\u003e \u003c\/tr\u003e \u003ctr\u003e \u003ctd\u003e\u003cstrong\u003ePack Size\u003c\/strong\u003e\u003c\/td\u003e \u003ctd\u003e15\/Box (105\/Case)\u003c\/td\u003e \u003c\/tr\u003e \u003ctr\u003e \u003ctd\u003e\u003cstrong\u003ePrice\u003c\/strong\u003e\u003c\/td\u003e \u003ctd\u003e$77.67 \/ Box ($0.7398 \/ lid)\u003c\/td\u003e \u003c\/tr\u003e \u003c\/tbody\u003e \u003c\/table\u003e \u003ch2\u003eTechnical Narrative\u003c\/h2\u003e \u003cp\u003eThe Caplugs® Evergreen is a 384-well Polystyrene (PS) microplate lid — the evaporation control solution for the small-volume 384-well format where edge-well evaporation is a more significant assay integrity risk than in 96-well format. The 20–120 µL working volume range of 384-well wells means a 5–10% evaporation event (which is acceptable in 96-well format) represents a 10–20 µL absolute volume loss per well — a concentration change that is assay-significant in HTS dose-response and enzyme kinetics applications. The PS lid maintains the humid microenvironment around each well to minimize this differential evaporation during incubation. Natural transparent PS allows visual plate monitoring without lid removal.\u003c\/p\u003e \u003cp\u003ePS is the standard lid material for aqueous ELISA, fluorescence, and luminescence 384-well plate incubation where DMSO exposure is minimal. The PS lid is autoclave-compatible for pre-sterilization before cell-based 384-well assays, though PP (290-8219-03L) provides better autoclave durability for repeated sterilization cycles at the same price point.\u003c\/p\u003e \u003cp\u003eAt $77.67 per Box of 15 — $0.7398 per lid — the delivers 384-well lid coverage at per-lid economics for high-throughput programs. Also available: 290-8219-03L (PP natural).\u003c\/p\u003e \u003ch2\u003eTechnical Specifications — Caplugs® Evergreen \u003c\/h2\u003e \u003ctable\u003e \u003cthead\u003e\u003ctr\u003e \u003cth\u003eSpecification\u003c\/th\u003e \u003cth\u003eValue\u003c\/th\u003e \u003c\/tr\u003e\u003c\/thead\u003e \u003ctbody\u003e \u003ctr\u003e \u003ctd\u003ePart Number\u003c\/td\u003e \u003ctd\u003e\u003c\/td\u003e \u003c\/tr\u003e \u003ctr\u003e \u003ctd\u003eCaplugs Item #\u003c\/td\u003e \u003ctd\u003e290821801LE1\u003c\/td\u003e \u003c\/tr\u003e \u003ctr\u003e \u003ctd\u003eWell Format\u003c\/td\u003e \u003ctd\u003e384-well SBS\/ANSI standard footprint\u003c\/td\u003e \u003c\/tr\u003e \u003ctr\u003e \u003ctd\u003eMaterial\u003c\/td\u003e \u003ctd\u003ePolystyrene (PS)\u003c\/td\u003e \u003c\/tr\u003e \u003ctr\u003e \u003ctd\u003eColor\u003c\/td\u003e \u003ctd\u003eNatural (transparent)\u003c\/td\u003e \u003c\/tr\u003e \u003ctr\u003e \u003ctd\u003eDMSO Compat.\u003c\/td\u003e \u003ctd\u003e✓ ≤10% (PS)\u003c\/td\u003e \u003c\/tr\u003e \u003ctr\u003e \u003ctd\u003eAutoclave\u003c\/td\u003e \u003ctd\u003e✓ Compatible (fewer cycles than PP)\u003c\/td\u003e \u003c\/tr\u003e \u003ctr\u003e \u003ctd\u003eSterility\u003c\/td\u003e \u003ctd\u003eNon-Sterile\u003c\/td\u003e \u003c\/tr\u003e \u003ctr\u003e \u003ctd\u003ePack Size\u003c\/td\u003e \u003ctd\u003e15\/Box (105\/Case)\u003c\/td\u003e \u003c\/tr\u003e \u003ctr\u003e \u003ctd\u003eApplication\u003c\/td\u003e \u003ctd\u003e384-well HTS plate incubation, compound plate storage, cell culture\u003c\/td\u003e \u003c\/tr\u003e \u003ctr\u003e \u003ctd\u003eBPA\/Phthalate\u003c\/td\u003e \u003ctd\u003eBPA-free; no phthalate plasticizers\u003c\/td\u003e \u003c\/tr\u003e \u003ctr\u003e \u003ctd\u003eCountry of Origin\u003c\/td\u003e \u003ctd\u003eMade in U.S.A. (California)\u003c\/td\u003e \u003c\/tr\u003e \u003c\/tbody\u003e \u003c\/table\u003e \u003ch2\u003e384-Well Lid Workflow Compatibility — PS\u003c\/h2\u003e \u003cp\u003eThe PS 384-well lid reduces evaporation from small-volume 384-well wells during incubation and storage. PS is the standard for aqueous 384-well cell culture and assay incubation:\u003c\/p\u003e \u003ctable\u003e \u003cthead\u003e\u003ctr\u003e \u003cth\u003eApplication\u003c\/th\u003e \u003cth\u003eAssay \/ Use\u003c\/th\u003e \u003cth\u003eNotes\u003c\/th\u003e \u003c\/tr\u003e\u003c\/thead\u003e \u003ctbody\u003e \u003ctr\u003e \u003ctd\u003e384-well plate incubation\u003c\/td\u003e \u003ctd\u003eCompound treatment, enzyme assay, cell culture\u003c\/td\u003e \u003ctd\u003eLid reduces evaporation from 384-well small well volume\u003c\/td\u003e \u003c\/tr\u003e \u003ctr\u003e \u003ctd\u003ePlate storage between runs\u003c\/td\u003e \u003ctd\u003eCovered storage during HTS batch processing\u003c\/td\u003e \u003ctd\u003eSmall 384-well volume requires lid to prevent edge-well desiccation\u003c\/td\u003e \u003c\/tr\u003e \u003ctr\u003e \u003ctd\u003e384-well cell culture\u003c\/td\u003e \u003ctd\u003eCovered incubation in CO2 incubator\u003c\/td\u003e \u003ctd\u003eLid maintains humid environment for cell-based 384-well assays\u003c\/td\u003e \u003c\/tr\u003e \u003ctr\u003e \u003ctd\u003eCompound plate protection\u003c\/td\u003e \u003ctd\u003eDMSO compound library plate covered storage\u003c\/td\u003e \u003ctd\u003ePP lid (290-8219-03L): broader DMSO tolerance than PS lid\u003c\/td\u003e \u003c\/tr\u003e \u003ctr\u003e \u003ctd\u003eOvernight incubation assays\u003c\/td\u003e \u003ctd\u003eAntibody or enzyme 4°C overnight sealed\u003c\/td\u003e \u003ctd\u003eLid reduces evaporation during extended 384-well incubation\u003c\/td\u003e \u003c\/tr\u003e \u003ctr\u003e \u003ctd\u003eTransport between instruments\u003c\/td\u003e \u003ctd\u003ePlate transport with contents covered\u003c\/td\u003e \u003ctd\u003eLid prevents contamination during robotic arm transfer\u003c\/td\u003e \u003c\/tr\u003e \u003c\/tbody\u003e \u003c\/table\u003e \u003cp\u003e\u003cem\u003e384-well wells hold only 20–120 µL — evaporation from edge wells is proportionally greater than in 96-well format. For extended incubations (\u0026gt;1 hour at 37°C), consider using EZ-Seal™ film (290-8200-MIC) for tighter sealing than a lid provides.\u003c\/em\u003e\u003c\/p\u003e \u003ch2\u003eChemical Resistance — Polystyrene (PS)\u003c\/h2\u003e \u003cp\u003ePS resists standard aqueous assay reagents. For DMSO-containing compound plates, PP lid (290-8219-03L) provides broader solvent tolerance.\u003c\/p\u003e \u003ctable\u003e \u003cthead\u003e\u003ctr\u003e \u003cth\u003eReagent \/ Condition\u003c\/th\u003e \u003cth\u003eCompatibility\u003c\/th\u003e \u003c\/tr\u003e\u003c\/thead\u003e \u003ctbody\u003e \u003ctr\u003e \u003ctd\u003eAqueous buffers\u003c\/td\u003e \u003ctd\u003e✓ Excellent\u003c\/td\u003e \u003c\/tr\u003e \u003ctr\u003e \u003ctd\u003eCell culture media\u003c\/td\u003e \u003ctd\u003e✓ Excellent\u003c\/td\u003e \u003c\/tr\u003e \u003ctr\u003e \u003ctd\u003eDMSO (≤10%)\u003c\/td\u003e \u003ctd\u003e✓ Good\u003c\/td\u003e \u003c\/tr\u003e \u003ctr\u003e \u003ctd\u003eShort-chain alcohols (brief)\u003c\/td\u003e \u003ctd\u003e✓ Good\u003c\/td\u003e \u003c\/tr\u003e \u003ctr\u003e \u003ctd\u003eFormalin (4%, brief)\u003c\/td\u003e \u003ctd\u003e✓ Good\u003c\/td\u003e \u003c\/tr\u003e \u003ctr\u003e \u003ctd\u003eAcetone\u003c\/td\u003e \u003ctd\u003e✗ Avoid\u003c\/td\u003e \u003c\/tr\u003e \u003ctr\u003e \u003ctd\u003eAutoclave\u003c\/td\u003e \u003ctd\u003e✗ Not compatible\u003c\/td\u003e \u003c\/tr\u003e \u003c\/tbody\u003e \u003c\/table\u003e \u003ch2\u003eLaboratory Applications\u003c\/h2\u003e \u003cp\u003eThe serves pharmaceutical HTS programs covering 384-well compound treatment plates during incubation; cell-based 384-well assay programs requiring covered incubation in CO2 incubators; ELISA and enzyme assay programs reducing edge-well evaporation during 384-well incubation; and any 384-well workflow requiring evaporation control without hermetic sealing.\u003c\/p\u003e \u003ch2\u003eU.S. Manufacturing, Quality \u0026amp; Institutional Procurement\u003c\/h2\u003e \u003cp\u003eEvery Caplugs® Evergreen lot is manufactured at our California facility and subject to rigorous quality inspection and material purity verification. We supply reference laboratories, hospital systems, biotech firms, and federal procurement offices under institutional pricing programs with blanket-order support and same-day shipping on stocked inventory. \u003ca href=\"#request-sample\"\u003eRequest a sample below\u003c\/a\u003e to validate before committing to volume.\u003c\/p\u003e \u003ch2\u003eFrequently Asked Questions — Caplugs® Evergreen \u003c\/h2\u003e \u003ch3\u003eWhat is the difference between the PS lid and a plate seal film for 384-well plates?\u003c\/h3\u003e \u003cp\u003eA lid (like the ) sits loosely on the plate — it reduces evaporation and blocks contamination while allowing gas exchange. An adhesive film seal (EZ-Seal™ 290-8200-MIC) bonds to the plate flange — providing hermetic sealing for PCR thermocycling, long-term storage, and brief centrifugation. For incubation periods under 2–4 hours at 37°C, a lid provides adequate evaporation control. For overnight incubation, PCR, or storage \u0026gt;24 hours, an adhesive film seal provides better protection against the differential edge-well evaporation that causes concentration artifacts in 384-well format.\u003c\/p\u003e \u003ch3\u003eWhat is the difference between the PS lid and the PP lid for 384-well plates?\u003c\/h3\u003e \u003cp\u003eBoth fit the same SBS-standard 384-well footprint at the same price. PP (290-8219-03L) provides broader DMSO tolerance (≤30% vs PS ≤10%) and better autoclave cycle durability for repeated sterilization. PS (, this product) provides slightly higher optical clarity for visual monitoring. For compound library plates or autoclave-sterilized workflows, PP is recommended.\u003c\/p\u003e \u003ch3\u003eAre the lids BPA-free?\u003c\/h3\u003e \u003cp\u003eYes. The is molded from virgin Polystyrene (PS) containing no BPA and no phthalate plasticizers.\u003c\/p\u003e \u003cscript type=\"application\/ld+json\"\u003e\n{\n  \"@context\": \"https:\/\/schema.org\",\n  \"@type\": \"Product\",\n  \"name\": \"384-Well Microplate Lids, Non-Sterile, Polystyrene (PS), Natural \\u2014 290-8218-01L | 15\/Box (105\/Case) | Caplugs\\u00ae Evergreen\",\n  \"description\": \"Caplugs\\u00ae Evergreen 290-8218-01L. 384-well microplate lids, PS natural, 15\/Box (105\/Case). Standard SBS 384-well fit. BPA-free. 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An adhesive film seal (EZ-Seal\\u2122 290-8200-MIC) bonds to the plate flange \\u2014 providing hermetic sealing for PCR thermocycling, long-term storage, and brief centrifugation. For incubation periods under 2\\u20134 hours at 37\\u00b0C, a lid provides adequate evaporation control. For overnight incubation, PCR, or storage \u003e24 hours, an adhesive film seal provides better protection against the differential edge-well evaporation that causes concentration artifacts in 384-well format.\"\n      }\n    },\n    {\n      \"@type\": \"Question\",\n      \"name\": \"What is the difference between the PS lid and the PP lid for 384-well plates?\",\n      \"acceptedAnswer\": {\n        \"@type\": \"Answer\",\n        \"text\": \"Both fit the same SBS-standard 384-well footprint at the same price. PP (290-8219-03L) provides broader DMSO tolerance (\\u226430% vs PS \\u226410%) and better autoclave cycle durability for repeated sterilization. PS (290-8218-01L, this product) provides slightly higher optical clarity for visual monitoring. For compound library plates or autoclave-sterilized workflows, PP is recommended.\"\n      }\n    },\n    {\n      \"@type\": \"Question\",\n      \"name\": \"Are the 290-8218-01L lids BPA-free?\",\n      \"acceptedAnswer\": {\n        \"@type\": \"Answer\",\n        \"text\": \"Yes. The 290-8218-01L is molded from virgin Polystyrene (PS) containing no BPA and no phthalate plasticizers.\"\n      }\n    }\n  ]\n}\n\u003c\/script\u003e","brand":"Caplugs® Evergreen","offers":[{"title":"Default Title","offer_id":48565329887464,"sku":"290-8218-01L","price":77.67,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0694\/5361\/1240\/files\/290-8218-01L_02.jpg?v=1778983990","url":"https:\/\/labsupplies.com\/products\/caplugs-290-8218-01l-384-well-microplate-lid-ps-natural","provider":"LabSupplies.com","version":"1.0","type":"link"}