{"product_id":"caplugs-258-4247-w90-biopsy-cassettes-acetal-1mm-holes-white","title":"Biopsy Cassettes, PP, White — 258-4247-W90 | 500\/Bag | Caplugs® Evergreen","description":"\u003ch2\u003eBiopsy Cassettes with Covers, 1.0 mm Holes, Acetal (POM), White — 258-4247-W90 | 500\/Bag Unassembled\u003c\/h2\u003e \u003ctable\u003e \u003cthead\u003e\u003ctr\u003e\u003cth colspan=\"2\"\u003eQuick Reference — 258-4247-W90\u003c\/th\u003e\u003c\/tr\u003e\u003c\/thead\u003e \u003ctbody\u003e \u003ctr\u003e \u003ctd\u003e\u003cstrong\u003eMaterial\u003c\/strong\u003e\u003c\/td\u003e \u003ctd\u003eAcetal (POM)\u003c\/td\u003e \u003c\/tr\u003e \u003ctr\u003e \u003ctd\u003e\u003cstrong\u003eColor\u003c\/strong\u003e\u003c\/td\u003e \u003ctd\u003eWhite\u003c\/td\u003e \u003c\/tr\u003e \u003ctr\u003e \u003ctd\u003e\u003cstrong\u003eHole Size\u003c\/strong\u003e\u003c\/td\u003e \u003ctd\u003e1.0 mm (small fragment retention)\u003c\/td\u003e \u003c\/tr\u003e \u003ctr\u003e \u003ctd\u003e\u003cstrong\u003eParaffin Compat.\u003c\/strong\u003e\u003c\/td\u003e \u003ctd\u003e✓ Excellent — acetal dimensional stability at 65°C\u003c\/td\u003e \u003c\/tr\u003e \u003ctr\u003e \u003ctd\u003e\u003cstrong\u003eXylene Compat.\u003c\/strong\u003e\u003c\/td\u003e \u003ctd\u003e✓ Excellent — superior xylene resistance vs PP\u003c\/td\u003e \u003c\/tr\u003e \u003ctr\u003e \u003ctd\u003e\u003cstrong\u003eAssembly\u003c\/strong\u003e\u003c\/td\u003e \u003ctd\u003eUnassembled — 500 cassettes + 500 covers per Bag\u003c\/td\u003e \u003c\/tr\u003e \u003ctr\u003e \u003ctd\u003e\u003cstrong\u003eSterility\u003c\/strong\u003e\u003c\/td\u003e \u003ctd\u003eNon-Sterile\u003c\/td\u003e \u003c\/tr\u003e \u003ctr\u003e \u003ctd\u003e\u003cstrong\u003ePack Size\u003c\/strong\u003e\u003c\/td\u003e \u003ctd\u003e500 \/ Bag\u003c\/td\u003e \u003c\/tr\u003e \u003ctr\u003e \u003ctd\u003e\u003cstrong\u003ePrice\u003c\/strong\u003e\u003c\/td\u003e \u003ctd\u003e$140.54 \/ Bag ($0.2811 \/ cassette + cover)\u003c\/td\u003e \u003c\/tr\u003e \u003c\/tbody\u003e \u003c\/table\u003e \u003ch2\u003eTechnical Narrative\u003c\/h2\u003e \u003cp\u003eThe Caplugs® Evergreen is a white Acetal (Polyoxymethylene, POM) biopsy cassette with 1.0 mm holes — engineered for the processing and embedding of small tissue specimens where fragment loss through standard 1.5–2.0 mm cassette holes is a documented pre-analytical error risk. The 1.0 mm aperture retains prostate needle cores, GI mucosal biopsy fragments, endocervical biopsies, and tiny shave and punch biopsy specimens that would pass through larger-hole cassettes during xylene clearing — the processing step where tissue dehydration reduces specimen dimensions and increases fragment mobility. White is the universal default for general biopsy processing and is compatible with all tissue-labeling methods including pencil, pen, and laser engraving on the cassette body.\u003c\/p\u003e \u003cp\u003eAcetal (POM) is specified over PP for small biopsy cassettes requiring maximum chemical resistance because POM's crystalline polymer structure provides superior xylene resistance, dimensional stability at paraffin wax infiltration temperatures (56–65°C), and resistance to warping or hole deformation under aggressive rapid-cycle tissue processor agitation. PP cassettes can exhibit subtle hole enlargement and dimensional creep under repeated xylene exposure and thermal cycling — a failure mode that increases fragment loss risk in high-throughput small biopsy programs. Acetal's higher crystallinity eliminates this degradation pathway, maintaining the 1.0 mm aperture geometry throughout the cassette service life.\u003c\/p\u003e \u003cp\u003eAt $140.54 per 500\/Bag — $0.2811 per cassette-and-cover pair — the delivers acetal-grade biopsy fragment security at bulk economics for high-volume small biopsy programs. Also available: 258-4248-G90 (Acetal Turquoise 1.0 mm, $140.54\/Bag).\u003c\/p\u003e \u003ch2\u003eTechnical Specifications — Caplugs® Evergreen \u003c\/h2\u003e \u003ctable\u003e \u003cthead\u003e\u003ctr\u003e \u003cth\u003eSpecification\u003c\/th\u003e \u003cth\u003eValue\u003c\/th\u003e \u003c\/tr\u003e\u003c\/thead\u003e \u003ctbody\u003e \u003ctr\u003e \u003ctd\u003ePart Number\u003c\/td\u003e \u003ctd\u003e\u003c\/td\u003e \u003c\/tr\u003e \u003ctr\u003e \u003ctd\u003eCaplugs Item #\u003c\/td\u003e \u003ctd\u003e2584247W90E1\u003c\/td\u003e \u003c\/tr\u003e \u003ctr\u003e \u003ctd\u003eMaterial\u003c\/td\u003e \u003ctd\u003eAcetal (POM) — Polyoxymethylene (POM)\u003c\/td\u003e \u003c\/tr\u003e \u003ctr\u003e \u003ctd\u003eColor\u003c\/td\u003e \u003ctd\u003eWhite\u003c\/td\u003e \u003c\/tr\u003e \u003ctr\u003e \u003ctd\u003eHole Size\u003c\/td\u003e \u003ctd\u003e1.0 mm (small biopsy fragment retention)\u003c\/td\u003e \u003c\/tr\u003e \u003ctr\u003e \u003ctd\u003eXylene Resistance\u003c\/td\u003e \u003ctd\u003e✓ Excellent — superior to PP cassettes\u003c\/td\u003e \u003c\/tr\u003e \u003ctr\u003e \u003ctd\u003eParaffin Compat.\u003c\/td\u003e \u003ctd\u003e✓ Excellent — dimensional stability at 56–65°C\u003c\/td\u003e \u003c\/tr\u003e \u003ctr\u003e \u003ctd\u003eFormalin Compat.\u003c\/td\u003e \u003ctd\u003e✓ Excellent\u003c\/td\u003e \u003c\/tr\u003e \u003ctr\u003e \u003ctd\u003eAssembly State\u003c\/td\u003e \u003ctd\u003eUnassembled — 500 cassettes + 500 covers per Bag\u003c\/td\u003e \u003c\/tr\u003e \u003ctr\u003e \u003ctd\u003eSterility\u003c\/td\u003e \u003ctd\u003eNon-Sterile\u003c\/td\u003e \u003c\/tr\u003e \u003ctr\u003e \u003ctd\u003ePack Size\u003c\/td\u003e \u003ctd\u003e500 \/ Bag\u003c\/td\u003e \u003c\/tr\u003e \u003ctr\u003e \u003ctd\u003eApplication\u003c\/td\u003e \u003ctd\u003eSmall biopsy, needle core, endoscopic biopsy tissue processing\u003c\/td\u003e \u003c\/tr\u003e \u003ctr\u003e \u003ctd\u003eBPA \/ Phthalate\u003c\/td\u003e \u003ctd\u003eBPA-free; no phthalate plasticizers\u003c\/td\u003e \u003c\/tr\u003e \u003ctr\u003e \u003ctd\u003eCountry of Origin\u003c\/td\u003e \u003ctd\u003eMade in U.S.A. (California)\u003c\/td\u003e \u003c\/tr\u003e \u003c\/tbody\u003e \u003c\/table\u003e \u003ch2\u003eSmall Biopsy Processing Compatibility — \u003c\/h2\u003e \u003cp\u003eThe acetal biopsy cassette with 1.0 mm holes is designed for small tissue fragments requiring maximum fragment retention during processing:\u003c\/p\u003e \u003ctable\u003e \u003cthead\u003e\u003ctr\u003e \u003cth\u003eApplication\u003c\/th\u003e \u003cth\u003eSpecimen \/ Use\u003c\/th\u003e \u003cth\u003eNotes\u003c\/th\u003e \u003c\/tr\u003e\u003c\/thead\u003e \u003ctbody\u003e \u003ctr\u003e \u003ctd\u003eSmall biopsy tissue processing\u003c\/td\u003e \u003ctd\u003eProstate needle core, GI mucosal biopsy, skin shave\u003c\/td\u003e \u003ctd\u003e1.0 mm holes retain small tissue fragments during processing\u003c\/td\u003e \u003c\/tr\u003e \u003ctr\u003e \u003ctd\u003eAutomated tissue processing\u003c\/td\u003e \u003ctd\u003eAll standard tissue processors — Leica, Thermo, Sakura\u003c\/td\u003e \u003ctd\u003eAcetal dimensional stability prevents warping at 65°C wax infiltration\u003c\/td\u003e \u003c\/tr\u003e \u003ctr\u003e \u003ctd\u003eCervical and endocervical biopsy\u003c\/td\u003e \u003ctd\u003eColposcopy biopsy, LEEP\/LLETZ specimen\u003c\/td\u003e \u003ctd\u003eSmall hole size prevents fragment loss during clearing steps\u003c\/td\u003e \u003c\/tr\u003e \u003ctr\u003e \u003ctd\u003eNeedle core archiving\u003c\/td\u003e \u003ctd\u003eProstate, liver, kidney, lung needle biopsy\u003c\/td\u003e \u003ctd\u003eCassette holds multiple cores in defined orientation for embedding\u003c\/td\u003e \u003c\/tr\u003e \u003ctr\u003e \u003ctd\u003eCytology cell block\u003c\/td\u003e \u003ctd\u003eCell pellet, pleural fluid, peritoneal washings\u003c\/td\u003e \u003ctd\u003eSmall holes prevent cell aggregate loss during processing\u003c\/td\u003e \u003c\/tr\u003e \u003ctr\u003e \u003ctd\u003eTiny specimen protocols\u003c\/td\u003e \u003ctd\u003eSub-millimeter endoscopic and punch biopsy fragments\u003c\/td\u003e \u003ctd\u003e1.0 mm hole is the smallest standard cassette aperture for fragment retention\u003c\/td\u003e \u003c\/tr\u003e \u003c\/tbody\u003e \u003c\/table\u003e \u003cp\u003e\u003cem\u003e1.0 mm holes are the smallest standard cassette aperture for routine tissue processing fragment retention. For sub-millimeter fragments, consider tissue biopsy foam pads as a secondary containment layer within the cassette.\u003c\/em\u003e\u003c\/p\u003e \u003ch2\u003eChemical \u0026amp; Processing Compatibility — Acetal (POM)\u003c\/h2\u003e \u003cp\u003eAcetal (POM) provides superior xylene and solvent resistance versus PP — making it the cassette material of choice for high-volume xylene-exposure processing protocols and laboratories running rapid clearance cycles.\u003c\/p\u003e \u003ctable\u003e \u003cthead\u003e\u003ctr\u003e \u003cth\u003eReagent \/ Condition\u003c\/th\u003e \u003cth\u003eCompatibility\u003c\/th\u003e \u003c\/tr\u003e\u003c\/thead\u003e \u003ctbody\u003e \u003ctr\u003e \u003ctd\u003eFormalin (10% NBF)\u003c\/td\u003e \u003ctd\u003e✓ Excellent — primary fixative, extended exposure\u003c\/td\u003e \u003c\/tr\u003e \u003ctr\u003e \u003ctd\u003eXylene \/ xylene substitutes\u003c\/td\u003e \u003ctd\u003e✓ Excellent — superior to PP for xylene resistance\u003c\/td\u003e \u003c\/tr\u003e \u003ctr\u003e \u003ctd\u003eEthanol (all concentrations)\u003c\/td\u003e \u003ctd\u003e✓ Excellent — dehydration series\u003c\/td\u003e \u003c\/tr\u003e \u003ctr\u003e \u003ctd\u003eIsopropanol (IPA)\u003c\/td\u003e \u003ctd\u003e✓ Excellent\u003c\/td\u003e \u003c\/tr\u003e \u003ctr\u003e \u003ctd\u003eParaffin wax (56–65°C)\u003c\/td\u003e \u003ctd\u003e✓ Excellent — dimensional stability at wax temp\u003c\/td\u003e \u003c\/tr\u003e \u003ctr\u003e \u003ctd\u003eFormic acid (decalcification)\u003c\/td\u003e \u003ctd\u003e✓ Good — 10–20% formic acid\u003c\/td\u003e \u003c\/tr\u003e \u003ctr\u003e \u003ctd\u003eEDTA (decalcification)\u003c\/td\u003e \u003ctd\u003e✓ Excellent\u003c\/td\u003e \u003c\/tr\u003e \u003ctr\u003e \u003ctd\u003eDilute acids (\u0026lt;10%)\u003c\/td\u003e \u003ctd\u003e✓ Good\u003c\/td\u003e \u003c\/tr\u003e \u003ctr\u003e \u003ctd\u003eDilute alkalies (pH \u0026lt;12)\u003c\/td\u003e \u003ctd\u003e✓ Good\u003c\/td\u003e \u003c\/tr\u003e \u003ctr\u003e \u003ctd\u003eAcetone (brief)\u003c\/td\u003e \u003ctd\u003e✓ Good\u003c\/td\u003e \u003c\/tr\u003e \u003c\/tbody\u003e \u003c\/table\u003e \u003cp\u003e\u003cem\u003eNot autoclave-compatible for cassette sterilization — histology cassettes are used with formalin-fixed non-sterile tissue and do not require sterilization before use.\u003c\/em\u003e\u003c\/p\u003e \u003ch2\u003eAnatomic Pathology Laboratory Applications\u003c\/h2\u003e \u003cp\u003eThe serves anatomic pathology programs with high prostate needle core biopsy volumes; gastrointestinal endoscopy programs processing small mucosal biopsy specimens; colposcopy and gynecologic pathology for cervical and endocervical biopsy; dermatopathology for punch biopsy and shave specimen processing; hepatology and nephrology for fine needle and core biopsy; cytopathology for cell block processing; and any histopathology setting where small tissue fragment loss in processing is a documented quality problem requiring smaller-hole cassette intervention.\u003c\/p\u003e \u003ch2\u003eU.S. Manufacturing, Quality \u0026amp; Institutional Procurement\u003c\/h2\u003e \u003cp\u003eEvery Caplugs® Evergreen lot is precision-molded at our California manufacturing facility and subject to rigorous dimensional inspection and material purity verification. We supply hospital systems, reference laboratories, and federal procurement offices under institutional pricing programs with blanket-order support and same-day shipping on stocked inventory. \u003ca href=\"#request-sample\"\u003eRequest a compatibility sample below\u003c\/a\u003e to validate fit with your processor configuration before committing to volume.\u003c\/p\u003e \u003ch2\u003eFrequently Asked Questions — Caplugs® Evergreen \u003c\/h2\u003e \u003ch3\u003eWhy are 1.0 mm holes specified for small biopsy cassettes?\u003c\/h3\u003e \u003cp\u003e1.0 mm is the smallest standard cassette aperture size used in routine histology processing for fragment retention. Prostate needle cores, GI mucosal biopsy fragments, and endocervical biopsies can measure 1–3 mm in cross-section after xylene dehydration reduces specimen dimensions — making standard 1.5–2.0 mm cassette holes a fragment loss risk. The 1.0 mm aperture retains specimens that would pass through larger holes during the clearing step. For sub-millimeter fragments, pair with a biopsy foam pad inside the cassette as a secondary containment layer.\u003c\/p\u003e \u003ch3\u003eWhy use Acetal (POM) instead of PP for small biopsy cassettes?\u003c\/h3\u003e \u003cp\u003eAcetal (POM) provides superior xylene resistance and dimensional stability versus PP at histology processing temperatures. PP cassettes can exhibit hole enlargement and dimensional creep under repeated xylene cycles and rapid thermal cycling — increasing fragment loss risk over the cassette service life. Acetal's crystalline polymer matrix resists this degradation, maintaining the 1.0 mm aperture geometry consistently across the full processing run. Acetal is specified by high-volume biopsy programs where dimensional stability is non-negotiable for small fragment retention.\u003c\/p\u003e \u003ch3\u003eIs the white color permanent through xylene and paraffin processing?\u003c\/h3\u003e \u003cp\u003eYes. The white pigmentation in the is compounded into the Acetal (POM) polymer matrix — not a surface coating. The color is stable through the full histology processing solvent sequence (formalin, ethanol, xylene, paraffin wax) without leaching, fading, or contaminating the embedding medium. Color stability through processing is essential for reliable color-coded specimen identification at the embedding station.\u003c\/p\u003e \u003cscript type=\"application\/ld+json\"\u003e\n{\n  \"@context\": \"https:\/\/schema.org\",\n  \"@type\": \"Product\",\n  \"name\": \"Biopsy Cassettes with Covers, 1.0 mm Holes, Non-Sterile, Acetal (POM), White \\u2014 258-4247-W90 | 500\/Bag Unassembled | Caplugs\\u00ae Evergreen\",\n  \"description\": \"Caplugs\\u00ae Evergreen 258-4247-W90. Acetal biopsy cassettes, 1.0 mm holes, white, 500\/Bag unassembled. Small fragment retention. BPA-free. USA.\",\n  \"sku\": \"2584247W90E1\",\n  \"mpn\": \"258-4247-W90\",\n  \"material\": \"Acetal (POM)\",\n  \"color\": \"White\",\n  \"brand\": {\n    \"@type\": \"Brand\",\n    \"name\": \"Caplugs\\u00ae Evergreen\"\n  },\n  \"manufacturer\": {\n    \"@type\": \"Organization\",\n    \"name\": \"Caplugs\\u00ae Evergreen\",\n    \"address\": {\n      \"@type\": \"PostalAddress\",\n      \"addressCountry\": \"US\",\n      \"addressRegion\": \"CA\"\n    }\n  },\n  \"offers\": {\n    \"@type\": \"Offer\",\n    \"price\": \"140.54\",\n    \"priceCurrency\": \"USD\",\n    \"availability\": \"https:\/\/schema.org\/InStock\",\n    \"itemCondition\": \"https:\/\/schema.org\/NewCondition\",\n    \"seller\": {\n      \"@type\": \"Organization\",\n      \"name\": \"LabSupplies\"\n    }\n  },\n  \"additionalProperty\": [\n    {\n      \"@type\": \"PropertyValue\",\n      \"name\": \"Pack Size\",\n      \"value\": \"500 \/ Bag\"\n    },\n    {\n      \"@type\": \"PropertyValue\",\n      \"name\": \"Sterility\",\n      \"value\": \"Non-Sterile\"\n    },\n    {\n      \"@type\": \"PropertyValue\",\n      \"name\": \"Country of Origin\",\n      \"value\": \"United States\"\n    },\n    {\n      \"@type\": \"PropertyValue\",\n      \"name\": \"BPA Free\",\n      \"value\": \"Yes\"\n    },\n    {\n      \"@type\": \"PropertyValue\",\n      \"name\": \"Paraffin Compatible\",\n      \"value\": \"Yes\"\n    }\n  ]\n}\n\u003c\/script\u003e \u003cscript type=\"application\/ld+json\"\u003e\n{\n  \"@context\": \"https:\/\/schema.org\",\n  \"@type\": \"FAQPage\",\n  \"mainEntity\": [\n    {\n      \"@type\": \"Question\",\n      \"name\": \"Why are 1.0 mm holes specified for small biopsy cassettes?\",\n      \"acceptedAnswer\": {\n        \"@type\": \"Answer\",\n        \"text\": \"1.0 mm is the smallest standard cassette aperture size used in routine histology processing for fragment retention. Prostate needle cores, GI mucosal biopsy fragments, and endocervical biopsies can measure 1\\u20133 mm in cross-section after xylene dehydration reduces specimen dimensions \\u2014 making standard 1.5\\u20132.0 mm cassette holes a fragment loss risk. The 1.0 mm aperture retains specimens that would pass through larger holes during the clearing step. For sub-millimeter fragments, pair with a biopsy foam pad inside the cassette as a secondary containment layer.\"\n      }\n    },\n    {\n      \"@type\": \"Question\",\n      \"name\": \"Why use Acetal (POM) instead of PP for small biopsy cassettes?\",\n      \"acceptedAnswer\": {\n        \"@type\": \"Answer\",\n        \"text\": \"Acetal (POM) provides superior xylene resistance and dimensional stability versus PP at histology processing temperatures. PP cassettes can exhibit hole enlargement and dimensional creep under repeated xylene cycles and rapid thermal cycling \\u2014 increasing fragment loss risk over the cassette service life. Acetal's crystalline polymer matrix resists this degradation, maintaining the 1.0 mm aperture geometry consistently across the full processing run. Acetal is specified by high-volume biopsy programs where dimensional stability is non-negotiable for small fragment retention.\"\n      }\n    },\n    {\n      \"@type\": \"Question\",\n      \"name\": \"Is the white color permanent through xylene and paraffin processing?\",\n      \"acceptedAnswer\": {\n        \"@type\": \"Answer\",\n        \"text\": \"Yes. The white pigmentation in the 258-4247-W90 is compounded into the Acetal (POM) polymer matrix \\u2014 not a surface coating. The color is stable through the full histology processing solvent sequence (formalin, ethanol, xylene, paraffin wax) without leaching, fading, or contaminating the embedding medium. Color stability through processing is essential for reliable color-coded specimen identification at the embedding station.\"\n      }\n    }\n  ]\n}\n\u003c\/script\u003e","brand":"Caplugs® Evergreen","offers":[{"title":"Default Title","offer_id":48564503183592,"sku":"258-4247-W90","price":140.54,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0694\/5361\/1240\/files\/258-4247-W90_02.jpg?v=1778941241","url":"https:\/\/labsupplies.com\/products\/caplugs-258-4247-w90-biopsy-cassettes-acetal-1mm-holes-white","provider":"LabSupplies.com","version":"1.0","type":"link"}