{"product_id":"caplugs-258-4014-y10-tissue-embedding-rings-hips-yellow","title":"Tissue Embedding Rings, PS, Yellow — 258-4014-Y10 | 500\/Bag | Caplugs® Evergreen","description":"\u003ch2\u003eTissue Embedding Rings, High Impact Polystyrene (HIPS), Yellow — 258-4014-Y10 | 500\/Bag\u003c\/h2\u003e \u003ctable\u003e \u003cthead\u003e\u003ctr\u003e\u003cth colspan=\"2\"\u003eQuick Reference — 258-4014-Y10\u003c\/th\u003e\u003c\/tr\u003e\u003c\/thead\u003e \u003ctbody\u003e \u003ctr\u003e \u003ctd\u003e\u003cstrong\u003eProduct\u003c\/strong\u003e\u003c\/td\u003e \u003ctd\u003eTissue Embedding Ring\u003c\/td\u003e \u003c\/tr\u003e \u003ctr\u003e \u003ctd\u003e\u003cstrong\u003eMaterial\u003c\/strong\u003e\u003c\/td\u003e \u003ctd\u003eHigh Impact Polystyrene (HIPS)\u003c\/td\u003e \u003c\/tr\u003e \u003ctr\u003e \u003ctd\u003e\u003cstrong\u003eColor\u003c\/strong\u003e\u003c\/td\u003e \u003ctd\u003eYellow\u003c\/td\u003e \u003c\/tr\u003e \u003ctr\u003e \u003ctd\u003e\u003cstrong\u003eParaffin Compat.\u003c\/strong\u003e\u003c\/td\u003e \u003ctd\u003e✓ Compatible (56–65°C)\u003c\/td\u003e \u003c\/tr\u003e \u003ctr\u003e \u003ctd\u003e\u003cstrong\u003eXylene Compat.\u003c\/strong\u003e\u003c\/td\u003e \u003ctd\u003e✓ Compatible\u003c\/td\u003e \u003c\/tr\u003e \u003ctr\u003e \u003ctd\u003e\u003cstrong\u003eFormalin Compat.\u003c\/strong\u003e\u003c\/td\u003e \u003ctd\u003e✓ Compatible\u003c\/td\u003e \u003c\/tr\u003e \u003ctr\u003e \u003ctd\u003e\u003cstrong\u003eSterility\u003c\/strong\u003e\u003c\/td\u003e \u003ctd\u003eNon-Sterile\u003c\/td\u003e \u003c\/tr\u003e \u003ctr\u003e \u003ctd\u003e\u003cstrong\u003ePack Size\u003c\/strong\u003e\u003c\/td\u003e \u003ctd\u003e500 \/ Bag\u003c\/td\u003e \u003c\/tr\u003e \u003ctr\u003e \u003ctd\u003e\u003cstrong\u003ePrice\u003c\/strong\u003e\u003c\/td\u003e \u003ctd\u003e$57.89 \/ Bag ($0.1158 \/ ring)\u003c\/td\u003e \u003c\/tr\u003e \u003c\/tbody\u003e \u003c\/table\u003e \u003ch2\u003eTechnical Narrative\u003c\/h2\u003e \u003cp\u003eThe Caplugs® Evergreen is a yellow High Impact Polystyrene (HIPS) tissue embedding ring — the consumable that holds the tissue cassette base in correct orientation within the embedding mold during paraffin infiltration at standard histology embedding center temperatures (56–65°C). The ring's precise dimensional fit with standard histology cassette bases ensures consistent tissue orientation and paraffin block face geometry — directly affecting section quality, ribbon continuity, and the number of diagnostic-quality levels obtainable per block. Yellow rings provide high-visibility contrast under both fluorescent and LED grossing bench lighting, and are used for priority or STAT specimen designation in pathology workflows requiring rapid turnaround identification.\u003c\/p\u003e \u003cp\u003eHigh Impact Polystyrene (HIPS) is specified over standard PS for tissue embedding rings because its rubber-toughened matrix withstands the thermal cycling, xylene exposure, and mechanical handling forces of histology tissue processing without the brittleness or cracking that limits standard PS at embedding temperatures. HIPS is compatible with the full histology solvent sequence — paraffin wax, xylene and xylene substitutes (HistoClear, Sub-X), all ethanol concentrations, IPA, and 10% NBF formalin — ensuring the ring maintains structural integrity throughout cassette processing, embedding, and block trimming workflows. The yellow pigmentation is compounded into the HIPS matrix — not a surface coating — ensuring permanent color retention through solvent exposure.\u003c\/p\u003e \u003cp\u003eAt $57.89 per 500\/Bag — $0.1158 per ring — the delivers high-throughput histopathology consumable economics for surgical pathology cores processing hundreds of blocks per shift. The complete Caplugs® Evergreen tissue embedding ring color range: 258-4010-W10 (White, $57.89\/Bag); 258-4011-P10 (Pink, $57.89\/Bag); 258-4012-B10 (Blue, $57.89\/Bag); 258-4013-G10 (Green, $57.89\/Bag) — enabling full color-scheme procurement from a single vendor for multi-category color-coded embedding programs.\u003c\/p\u003e \u003ch2\u003eTechnical Specifications — Caplugs® Evergreen \u003c\/h2\u003e \u003ctable\u003e \u003cthead\u003e\u003ctr\u003e \u003cth\u003eSpecification\u003c\/th\u003e \u003cth\u003eValue\u003c\/th\u003e \u003c\/tr\u003e\u003c\/thead\u003e \u003ctbody\u003e \u003ctr\u003e \u003ctd\u003ePart Number\u003c\/td\u003e \u003ctd\u003e\u003c\/td\u003e \u003c\/tr\u003e \u003ctr\u003e \u003ctd\u003eCaplugs Item #\u003c\/td\u003e \u003ctd\u003e2584014Y10E1\u003c\/td\u003e \u003c\/tr\u003e \u003ctr\u003e \u003ctd\u003eProduct Type\u003c\/td\u003e \u003ctd\u003eTissue Embedding Ring\u003c\/td\u003e \u003c\/tr\u003e \u003ctr\u003e \u003ctd\u003eMaterial\u003c\/td\u003e \u003ctd\u003eHigh Impact Polystyrene (HIPS)\u003c\/td\u003e \u003c\/tr\u003e \u003ctr\u003e \u003ctd\u003eColor\u003c\/td\u003e \u003ctd\u003eYellow\u003c\/td\u003e \u003c\/tr\u003e \u003ctr\u003e \u003ctd\u003eParaffin Compat.\u003c\/td\u003e \u003ctd\u003e✓ Compatible at standard embedding temperatures (56–65°C)\u003c\/td\u003e \u003c\/tr\u003e \u003ctr\u003e \u003ctd\u003eXylene Compat.\u003c\/td\u003e \u003ctd\u003e✓ Compatible\u003c\/td\u003e \u003c\/tr\u003e \u003ctr\u003e \u003ctd\u003eFormalin Compat.\u003c\/td\u003e \u003ctd\u003e✓ Compatible (10% NBF)\u003c\/td\u003e \u003c\/tr\u003e \u003ctr\u003e \u003ctd\u003eSterility\u003c\/td\u003e \u003ctd\u003eNon-Sterile\u003c\/td\u003e \u003c\/tr\u003e \u003ctr\u003e \u003ctd\u003ePack Size\u003c\/td\u003e \u003ctd\u003e500 \/ Bag\u003c\/td\u003e \u003c\/tr\u003e \u003ctr\u003e \u003ctd\u003eReorder Unit\u003c\/td\u003e \u003ctd\u003eBag of 500\u003c\/td\u003e \u003c\/tr\u003e \u003ctr\u003e \u003ctd\u003eApplication\u003c\/td\u003e \u003ctd\u003eHistopathology tissue embedding, surgical biopsy, frozen section\u003c\/td\u003e \u003c\/tr\u003e \u003ctr\u003e \u003ctd\u003eBPA \/ Phthalate\u003c\/td\u003e \u003ctd\u003eBPA-free; no phthalate plasticizers\u003c\/td\u003e \u003c\/tr\u003e \u003ctr\u003e \u003ctd\u003eCountry of Origin\u003c\/td\u003e \u003ctd\u003eMade in U.S.A. (California)\u003c\/td\u003e \u003c\/tr\u003e \u003c\/tbody\u003e \u003c\/table\u003e \u003ch2\u003eHistopathology Workflow Compatibility — \u003c\/h2\u003e \u003cp\u003eThe yellow HIPS tissue embedding ring is compatible with standard paraffin embedding workflows across the following specimen types and applications:\u003c\/p\u003e \u003ctable\u003e \u003cthead\u003e\u003ctr\u003e \u003cth\u003eApplication\u003c\/th\u003e \u003cth\u003eSpecimen Types\u003c\/th\u003e \u003cth\u003eNotes\u003c\/th\u003e \u003c\/tr\u003e\u003c\/thead\u003e \u003ctbody\u003e \u003ctr\u003e \u003ctd\u003eSurgical biopsy embedding\u003c\/td\u003e \u003ctd\u003eProstate needle core, cervical biopsy, skin punch\u003c\/td\u003e \u003ctd\u003eRing holds cassette-base position during paraffin infiltration\u003c\/td\u003e \u003c\/tr\u003e \u003ctr\u003e \u003ctd\u003eEndoscopic biopsy\u003c\/td\u003e \u003ctd\u003eGI mucosal biopsy, esophageal, gastric specimens\u003c\/td\u003e \u003ctd\u003eSmall ring format accommodates endoscopic biopsy cassette sizes\u003c\/td\u003e \u003c\/tr\u003e \u003ctr\u003e \u003ctd\u003eExcisional specimen embedding\u003c\/td\u003e \u003ctd\u003eBreast lumpectomy, melanoma excision, lymph node\u003c\/td\u003e \u003ctd\u003eRing maintains orientation during embedding at wax station\u003c\/td\u003e \u003c\/tr\u003e \u003ctr\u003e \u003ctd\u003eNeedle core and TRUS biopsy\u003c\/td\u003e \u003ctd\u003eProstate, liver, kidney, thyroid needle cores\u003c\/td\u003e \u003ctd\u003eColor coding enables laterality and site designation per core\u003c\/td\u003e \u003c\/tr\u003e \u003ctr\u003e \u003ctd\u003eFrozen section support\u003c\/td\u003e \u003ctd\u003eIntraoperative margin and sentinel node\u003c\/td\u003e \u003ctd\u003eRing used in fresh tissue embedding for cryostat sectioning\u003c\/td\u003e \u003c\/tr\u003e \u003ctr\u003e \u003ctd\u003eResearch tissue microarray (TMA)\u003c\/td\u003e \u003ctd\u003eMulti-core donor block embedding\u003c\/td\u003e \u003ctd\u003ePrecision ring positioning enables consistent core depth for TMA\u003c\/td\u003e \u003c\/tr\u003e \u003ctr\u003e \u003ctd\u003eCytology cell block\u003c\/td\u003e \u003ctd\u003eCell pellet, peritoneal fluid, BAL\u003c\/td\u003e \u003ctd\u003eRing contains paraffin cell block during embedding\u003c\/td\u003e \u003c\/tr\u003e \u003ctr\u003e \u003ctd\u003eVeterinary histopathology\u003c\/td\u003e \u003ctd\u003eAnimal tissue biopsy, necropsy specimens\u003c\/td\u003e \u003ctd\u003eSame embedding ring format as human histopathology\u003c\/td\u003e \u003c\/tr\u003e \u003c\/tbody\u003e \u003c\/table\u003e \u003cp\u003e\u003cem\u003eTissue embedding rings are designed for use with standard histology cassettes and embedding centers (Leica EG1150, Thermo Shandon Histocentre, Sakura Tissue-Tek). Confirm ring-to-cassette fit with a sample before bulk purchase if using non-standard cassette formats.\u003c\/em\u003e\u003c\/p\u003e \u003ch2\u003eChemical \u0026amp; Processing Compatibility — High Impact Polystyrene (HIPS)\u003c\/h2\u003e \u003cp\u003eThe is molded from High Impact Polystyrene (HIPS) — selected over standard PS for its enhanced toughness and resistance to the solvents used in histology tissue processing. HIPS withstands the full histology processing solvent sequence without warping or cracking.\u003c\/p\u003e \u003ctable\u003e \u003cthead\u003e\u003ctr\u003e \u003cth\u003eReagent \/ Condition\u003c\/th\u003e \u003cth\u003eHIPS Compatibility\u003c\/th\u003e \u003c\/tr\u003e\u003c\/thead\u003e \u003ctbody\u003e \u003ctr\u003e \u003ctd\u003eParaffin wax (56–65°C)\u003c\/td\u003e \u003ctd\u003e✓ Compatible — primary embedding medium\u003c\/td\u003e \u003c\/tr\u003e \u003ctr\u003e \u003ctd\u003eXylene \/ xylene substitute\u003c\/td\u003e \u003ctd\u003e✓ Compatible — standard tissue processing solvent\u003c\/td\u003e \u003c\/tr\u003e \u003ctr\u003e \u003ctd\u003eEthanol (all concentrations)\u003c\/td\u003e \u003ctd\u003e✓ Compatible — tissue dehydration series\u003c\/td\u003e \u003c\/tr\u003e \u003ctr\u003e \u003ctd\u003eIsopropanol (IPA)\u003c\/td\u003e \u003ctd\u003e✓ Compatible\u003c\/td\u003e \u003c\/tr\u003e \u003ctr\u003e \u003ctd\u003eFormalin (10% buffered)\u003c\/td\u003e \u003ctd\u003e✓ Compatible — standard tissue fixative\u003c\/td\u003e \u003c\/tr\u003e \u003ctr\u003e \u003ctd\u003eHematoxylin \/ eosin staining\u003c\/td\u003e \u003ctd\u003e✓ Compatible — ring does not contact staining baths\u003c\/td\u003e \u003c\/tr\u003e \u003ctr\u003e \u003ctd\u003eAcetone (brief contact)\u003c\/td\u003e \u003ctd\u003e✓ Good — brief incidental contact\u003c\/td\u003e \u003c\/tr\u003e \u003ctr\u003e \u003ctd\u003eConcentrated organic solvents\u003c\/td\u003e \u003ctd\u003e✓ Good — HIPS has better solvent resistance than standard PS\u003c\/td\u003e \u003c\/tr\u003e \u003ctr\u003e \u003ctd\u003eAutoclave (121°C \/ 15 psi)\u003c\/td\u003e \u003ctd\u003e✗ Not recommended — HIPS softens at embedding wax temps\u003c\/td\u003e \u003c\/tr\u003e \u003c\/tbody\u003e \u003c\/table\u003e \u003cp\u003e\u003cem\u003eHIPS is rated for standard histology embedding center operating temperatures (56–65°C). Do not expose to temperatures above 75°C. Not autoclave-compatible.\u003c\/em\u003e\u003c\/p\u003e \u003ch2\u003eAnatomic Pathology Laboratory Applications\u003c\/h2\u003e \u003cp\u003eThe yellow tissue embedding ring serves hospital and reference anatomic pathology laboratories for surgical biopsy, excisional specimen, and resection block embedding; gastrointestinal and endoscopy pathology programs for mucosal biopsy embedding; genitourinary pathology for prostate needle core, bladder, and kidney biopsy processing; dermatopathology for punch and shave biopsy embedding; breast pathology for core needle and excisional specimen blocks; neuropathology and research histology for CNS tissue processing; veterinary diagnostic laboratories; and any pathology setting using color-coded embedding rings to designate specimen type, anatomic site, laterality, or processing priority. The 500\/Bag format suits high-volume surgical pathology cores.\u003c\/p\u003e \u003ch2\u003eU.S. Manufacturing, Quality \u0026amp; Institutional Procurement\u003c\/h2\u003e \u003cp\u003eEvery Caplugs® Evergreen lot is precision-molded at our California manufacturing facility and subject to rigorous dimensional inspection and material purity verification. We supply reference laboratories, hospital systems, and federal procurement offices under institutional pricing programs with blanket-order support and same-day shipping on stocked inventory. \u003ca href=\"#request-sample\"\u003eRequest a compatibility sample below\u003c\/a\u003e to validate fit with your cassette format before committing to volume.\u003c\/p\u003e \u003ch2\u003eFrequently Asked Questions — Caplugs® Evergreen \u003c\/h2\u003e \u003ch3\u003eWhat histology cassette formats are compatible with the embedding ring?\u003c\/h3\u003e \u003cp\u003eThe is designed for standard histology tissue cassettes used on Leica EG1150, Thermo Shandon Histocentre, and Sakura Tissue-Tek embedding centers. Always confirm ring-to-cassette fit with a sample set before large-volume purchase — cassette base dimensions vary slightly between manufacturers and can affect ring seating depth and paraffin block face geometry.\u003c\/p\u003e \u003ch3\u003eWhy use HIPS rather than standard PS for tissue embedding rings?\u003c\/h3\u003e \u003cp\u003eHigh Impact Polystyrene (HIPS) is a rubber-toughened grade of PS that provides significantly better impact resistance and solvent toughness than standard PS at histology processing temperatures. Standard PS can become brittle and crack during xylene and ethanol exposure at embedding center temperatures (56–65°C). HIPS maintains structural integrity across the full histology solvent and temperature cycle — paraffin wax, xylene, all ethanol concentrations, and NBF formalin — without warping or releasing fragments into the embedding mold that could contaminate the paraffin block.\u003c\/p\u003e \u003ch3\u003eIs the yellow color permanent through xylene and paraffin processing?\u003c\/h3\u003e \u003cp\u003eYes. The yellow pigmentation in the is compounded directly into the HIPS polymer matrix — not applied as a surface coating or dye. This means the color is stable through xylene, ethanol, formalin, and paraffin wax exposure without leaching, fading, or contaminating the embedding medium. Color stability through the full processing cycle is essential for reliable color-coded specimen identification at the embedding station.\u003c\/p\u003e \u003cscript type=\"application\/ld+json\"\u003e\n{\n  \"@context\": \"https:\/\/schema.org\",\n  \"@type\": \"Product\",\n  \"name\": \"Tissue Embedding Rings, Non-Sterile, High Impact Polystyrene (HIPS), Yellow \\u2014 258-4014-Y10 | 500\/Bag | Caplugs\\u00ae Evergreen\",\n  \"description\": \"Caplugs\\u00ae Evergreen 258-4014-Y10. Tissue embedding rings, HIPS yellow, 500\/Bag. Paraffin-compatible. Histopathology, surgical biopsy. BPA-free. USA.\",\n  \"sku\": \"2584014Y10E1\",\n  \"mpn\": \"258-4014-Y10\",\n  \"material\": \"High Impact Polystyrene (HIPS)\",\n  \"color\": \"Yellow\",\n  \"brand\": {\n    \"@type\": \"Brand\",\n    \"name\": \"Caplugs\\u00ae Evergreen\"\n  },\n  \"manufacturer\": {\n    \"@type\": \"Organization\",\n    \"name\": \"Caplugs\\u00ae Evergreen\",\n    \"address\": {\n      \"@type\": \"PostalAddress\",\n      \"addressCountry\": \"US\",\n      \"addressRegion\": \"CA\"\n    }\n  },\n  \"offers\": {\n    \"@type\": \"Offer\",\n    \"price\": \"57.89\",\n    \"priceCurrency\": \"USD\",\n    \"availability\": \"https:\/\/schema.org\/InStock\",\n    \"itemCondition\": \"https:\/\/schema.org\/NewCondition\",\n    \"seller\": {\n      \"@type\": \"Organization\",\n      \"name\": \"LabSupplies\"\n    }\n  },\n  \"additionalProperty\": [\n    {\n      \"@type\": \"PropertyValue\",\n      \"name\": \"Pack Size\",\n      \"value\": \"500 \/ Bag\"\n    },\n    {\n      \"@type\": \"PropertyValue\",\n      \"name\": \"Sterility\",\n      \"value\": \"Non-Sterile\"\n    },\n    {\n      \"@type\": \"PropertyValue\",\n      \"name\": \"Paraffin Compatible\",\n      \"value\": \"Yes\"\n    },\n    {\n      \"@type\": \"PropertyValue\",\n      \"name\": \"Country of Origin\",\n      \"value\": \"United States\"\n    },\n    {\n      \"@type\": \"PropertyValue\",\n      \"name\": \"BPA Free\",\n      \"value\": \"Yes\"\n    }\n  ]\n}\n\u003c\/script\u003e \u003cscript type=\"application\/ld+json\"\u003e\n{\n  \"@context\": \"https:\/\/schema.org\",\n  \"@type\": \"FAQPage\",\n  \"mainEntity\": [\n    {\n      \"@type\": \"Question\",\n      \"name\": \"What histology cassette formats are compatible with the 258-4014-Y10 embedding ring?\",\n      \"acceptedAnswer\": {\n        \"@type\": \"Answer\",\n        \"text\": \"The 258-4014-Y10 is designed for standard histology tissue cassettes used on Leica EG1150, Thermo Shandon Histocentre, and Sakura Tissue-Tek embedding centers. Always confirm ring-to-cassette fit with a sample set before large-volume purchase \\u2014 cassette base dimensions vary slightly between manufacturers and can affect ring seating depth and paraffin block face geometry.\"\n      }\n    },\n    {\n      \"@type\": \"Question\",\n      \"name\": \"Why use HIPS rather than standard PS for tissue embedding rings?\",\n      \"acceptedAnswer\": {\n        \"@type\": \"Answer\",\n        \"text\": \"High Impact Polystyrene (HIPS) is a rubber-toughened grade of PS that provides significantly better impact resistance and solvent toughness than standard PS at histology processing temperatures. Standard PS can become brittle and crack during xylene and ethanol exposure at embedding center temperatures (56\\u201365\\u00b0C). HIPS maintains structural integrity across the full histology solvent and temperature cycle \\u2014 paraffin wax, xylene, all ethanol concentrations, and NBF formalin \\u2014 without warping or releasing fragments into the embedding mold that could contaminate the paraffin block.\"\n      }\n    },\n    {\n      \"@type\": \"Question\",\n      \"name\": \"Is the yellow color permanent through xylene and paraffin processing?\",\n      \"acceptedAnswer\": {\n        \"@type\": \"Answer\",\n        \"text\": \"Yes. The yellow pigmentation in the 258-4014-Y10 is compounded directly into the HIPS polymer matrix \\u2014 not applied as a surface coating or dye. This means the color is stable through xylene, ethanol, formalin, and paraffin wax exposure without leaching, fading, or contaminating the embedding medium. Color stability through the full processing cycle is essential for reliable color-coded specimen identification at the embedding station.\"\n      }\n    }\n  ]\n}\n\u003c\/script\u003e","brand":"Caplugs® Evergreen","offers":[{"title":"Default Title","offer_id":48564494565608,"sku":"258-4014-Y10","price":57.89,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0694\/5361\/1240\/files\/Embedding_20Rings_3.png?v=1778940878","url":"https:\/\/labsupplies.com\/products\/caplugs-258-4014-y10-tissue-embedding-rings-hips-yellow","provider":"LabSupplies.com","version":"1.0","type":"link"}