{"product_id":"222-8664-08n-deep-well-microplate","title":"1.0 mL Deep Well Microplates, Chamfered, PPC, Natural — 222-8664-08N | 5\/Bag | Caplugs® Evergreen","description":"\u003ch2\u003eQuick Reference\u003c\/h2\u003e \u003ctable\u003e \u003ctbody\u003e \u003ctr\u003e \u003cth\u003ePart Number\u003c\/th\u003e \u003ctd\u003e222-8664-08N\u003c\/td\u003e \u003c\/tr\u003e \u003ctr\u003e \u003cth\u003eFormat\u003c\/th\u003e \u003ctd\u003e96-well deep well microplate\u003c\/td\u003e \u003c\/tr\u003e \u003ctr\u003e \u003cth\u003eWell Bottom\u003c\/th\u003e \u003ctd\u003eTapered\u003c\/td\u003e \u003c\/tr\u003e \u003ctr\u003e \u003cth\u003eWell Geometry\u003c\/th\u003e \u003ctd\u003eTapered conical well — concentrates sample at base for efficient aspiration\u003c\/td\u003e \u003c\/tr\u003e \u003ctr\u003e \u003cth\u003eWell Volume\u003c\/th\u003e \u003ctd\u003e1.0 mL (1000 µL) per well\u003c\/td\u003e \u003c\/tr\u003e \u003ctr\u003e \u003cth\u003eMaterial\u003c\/th\u003e \u003ctd\u003ePolypropylene Copolymer (PPC)\u003c\/td\u003e \u003c\/tr\u003e \u003ctr\u003e \u003cth\u003eColor\u003c\/th\u003e \u003ctd\u003eNatural\u003c\/td\u003e \u003c\/tr\u003e \u003ctr\u003e \u003cth\u003eSterility\u003c\/th\u003e \u003ctd\u003eSterile\u003c\/td\u003e \u003c\/tr\u003e \u003ctr\u003e \u003cth\u003ePack Size\u003c\/th\u003e \u003ctd\u003e5\/Bag\u003c\/td\u003e \u003c\/tr\u003e \u003ctr\u003e \u003cth\u003ePrimary Use\u003c\/th\u003e \u003ctd\u003eLC-MS sample prep, SPE, LLE, protein precipitation, compound storage\u003c\/td\u003e \u003c\/tr\u003e \u003ctr\u003e \u003cth\u003eOrigin\u003c\/th\u003e \u003ctd\u003eMade in USA\u003c\/td\u003e \u003c\/tr\u003e \u003ctr\u003e \u003cth\u003ePrice\u003c\/th\u003e \u003ctd\u003e$93.73\/Bag ($18.7450\/plate)\u003c\/td\u003e \u003c\/tr\u003e \u003c\/tbody\u003e \u003c\/table\u003e \u003ch2\u003eTechnical Narrative\u003c\/h2\u003e \u003cp\u003eThe Caplugs® Evergreen \u003cstrong\u003e222-8664-08N\u003c\/strong\u003e is a \u003cstrong\u003e96-Well Deep Well PPC Microplate, Tapered Bottom\u003c\/strong\u003e, 1.0 mL per well, Sterile, 5\/Bag. The 1.0 mL well volume is the standard deep well volume for most LC-MS sample preparation workflows — accommodating the full sample volume plus precipitation or extraction solvent at standard protocol ratios (1:2 or 1:3 sample:solvent). The tapered well bottom narrows to a smaller-diameter base — concentrating the sample at the well tip for more complete aspiration of small residual volumes after extraction or centrifugation.\u003c\/p\u003e \u003cp\u003ePPC provides the critical material advantage for deep well LC-MS sample preparation: full compatibility with acetonitrile, methanol, ethyl acetate, and other organic extraction solvents used in protein precipitation, liquid-liquid extraction (LLE), and SPE elution steps that would crack or swell standard PS deep well plates under prolonged organic solvent exposure. BPA-free, phthalate-free, FDA-compliant, \u003c\/p\u003e \u003cp\u003eProcurement economics: \u003cstrong\u003e$93.73\/Bag (5 plates)\u003c\/strong\u003e, \u003cstrong\u003e$18.7450\/plate\u003c\/strong\u003e. Siblings: \u003cstrong\u003e222-8662-01N\u003c\/strong\u003e (1.0 mL PS Tapered Sterile 5\/Bag); \u003cstrong\u003e222-8668-08C\u003c\/strong\u003e (2.0 mL PPC Chamfered Sterile 5\/Bag); \u003cstrong\u003e222-8649-080\u003c\/strong\u003e (0.5 mL PPC Tapered Non-Sterile 5\/Bag). LabSupplies.com ships from USA inventory, typically same business day.\u003c\/p\u003e \u003ch2\u003eTechnical Specifications\u003c\/h2\u003e \u003ctable\u003e \u003ctbody\u003e \u003ctr\u003e \u003cth\u003ePart Number\u003c\/th\u003e \u003ctd\u003e\u003c\/td\u003e \u003c\/tr\u003e \u003ctr\u003e \u003cth\u003eCaplugs Item #\u003c\/th\u003e \u003ctd\u003e\u003c\/td\u003e \u003c\/tr\u003e \u003ctr\u003e \u003cth\u003eFormat\u003c\/th\u003e \u003ctd\u003e96-well deep well microplate\u003c\/td\u003e \u003c\/tr\u003e \u003ctr\u003e \u003cth\u003eWell Bottom\u003c\/th\u003e \u003ctd\u003eTapered\u003c\/td\u003e \u003c\/tr\u003e \u003ctr\u003e \u003cth\u003eWell Volume\u003c\/th\u003e \u003ctd\u003e1.0 mL (1000 µL) per well\u003c\/td\u003e \u003c\/tr\u003e \u003ctr\u003e \u003cth\u003eMaterial\u003c\/th\u003e \u003ctd\u003ePolypropylene Copolymer (PPC)\u003c\/td\u003e \u003c\/tr\u003e \u003ctr\u003e \u003cth\u003eColor\u003c\/th\u003e \u003ctd\u003eNatural\u003c\/td\u003e \u003c\/tr\u003e \u003ctr\u003e \u003cth\u003eSterility\u003c\/th\u003e \u003ctd\u003eSterile\u003c\/td\u003e \u003c\/tr\u003e \u003ctr\u003e \u003cth\u003ePack Size\u003c\/th\u003e \u003ctd\u003e5\/Bag\u003c\/td\u003e \u003c\/tr\u003e \u003ctr\u003e \u003cth\u003eSolvent Compatibility\u003c\/th\u003e \u003ctd\u003eFull ACN\/MeOH\/EtOAc organic solvent compatible (PPC)\u003c\/td\u003e \u003c\/tr\u003e \u003ctr\u003e \u003cth\u003eApplication\u003c\/th\u003e \u003ctd\u003eLC-MS sample prep, SPE, LLE, protein precipitation, compound storage\u003c\/td\u003e \u003c\/tr\u003e \u003ctr\u003e \u003cth\u003eBPA \/ Phthalate\u003c\/th\u003e \u003ctd\u003eBPA-Free, Phthalate-Free, Latex-Free\u003c\/td\u003e \u003c\/tr\u003e \u003ctr\u003e \u003cth\u003eCountry of Origin\u003c\/th\u003e \u003ctd\u003eUSA \u003c\/td\u003e \u003c\/tr\u003e \u003ctr\u003e \u003cth\u003ePrice\u003c\/th\u003e \u003ctd\u003e$93.73\/Bag ($18.7450\/plate)\u003c\/td\u003e \u003c\/tr\u003e \u003c\/tbody\u003e \u003c\/table\u003e \u003ch2\u003e96-Well Deep Well Microplate (Tapered, 1.0 mL, PPC) Applications\u003c\/h2\u003e \u003cp\u003eThe is compatible with the following sample preparation and high-throughput workflows.\u003c\/p\u003e \u003ctable\u003e \u003cthead\u003e\u003ctr\u003e \u003cth\u003eApplication\u003c\/th\u003e \u003cth\u003eSetting \/ Configuration\u003c\/th\u003e \u003cth\u003eNotes\u003c\/th\u003e \u003c\/tr\u003e\u003c\/thead\u003e \u003ctbody\u003e \u003ctr\u003e \u003cth\u003eProtein precipitation (LC-MS)\u003c\/th\u003e \u003ctd\u003eAdd ACN\/MeOH to plasma, centrifuge, aspirate\u003c\/td\u003e \u003ctd\u003ePPC: full ACN\/MeOH compatibility\u003c\/td\u003e \u003c\/tr\u003e \u003ctr\u003e \u003cth\u003eLiquid-liquid extraction (LLE)\u003c\/th\u003e \u003ctd\u003eAdd organic extractant, mix, phase separate\u003c\/td\u003e \u003ctd\u003e1.0 mL: sufficient for sample + extractant at standard LLE ratios\u003c\/td\u003e \u003c\/tr\u003e \u003ctr\u003e \u003cth\u003eSPE elution collection\u003c\/th\u003e \u003ctd\u003eCollect SPE eluate in deep well plate\u003c\/td\u003e \u003ctd\u003ePPC: organic eluent compatible\u003c\/td\u003e \u003c\/tr\u003e \u003ctr\u003e \u003cth\u003eCompound library storage\u003c\/th\u003e \u003ctd\u003eDMSO compound stocks, —20°C or —80°C\u003c\/td\u003e \u003ctd\u003eDeep well for higher-volume compound stocks per well\u003c\/td\u003e \u003c\/tr\u003e \u003ctr\u003e \u003cth\u003eAutomated liquid handling\u003c\/th\u003e \u003ctd\u003eRobot-compatible SBS footprint\u003c\/td\u003e \u003ctd\u003eTapered bottom: designed for liquid handler tip access\u003c\/td\u003e \u003c\/tr\u003e \u003ctr\u003e \u003cth\u003eCell-based prep (large volume)\u003c\/th\u003e \u003ctd\u003eCell lysis, extraction, 96-well scale\u003c\/td\u003e \u003ctd\u003e1.0 mL accommodates lysis volume + supernatant\u003c\/td\u003e \u003c\/tr\u003e \u003ctr\u003e \u003cth\u003eDried blood spot (DBS) elution\u003c\/th\u003e \u003ctd\u003eDBS punch elution into deep well\u003c\/td\u003e \u003ctd\u003eDeep well accommodates elution volume for DBS extraction\u003c\/td\u003e \u003c\/tr\u003e \u003c\/tbody\u003e \u003c\/table\u003e \u003ch2\u003eChemical Resistance — Polypropylene Copolymer (PPC) Deep Well Microplate\u003c\/h2\u003e \u003cp\u003eCompatibility for PPC — key organic solvent compatibility differences between PS and PPC are highlighted.\u003c\/p\u003e \u003ctable\u003e \u003cthead\u003e\u003ctr\u003e \u003cth\u003eReagent \/ Condition\u003c\/th\u003e \u003cth\u003eCompatibility\u003c\/th\u003e \u003cth\u003eNotes\u003c\/th\u003e \u003c\/tr\u003e\u003c\/thead\u003e \u003ctbody\u003e \u003ctr\u003e \u003ctd\u003eAcetonitrile (\u0026lt;100%)\u003c\/td\u003e \u003ctd\u003eExcellent\u003c\/td\u003e \u003ctd\u003ePPC: full ACN compatibility — key advantage for LC-MS protein precipitation.\u003c\/td\u003e \u003c\/tr\u003e \u003ctr\u003e \u003ctd\u003eMethanol (\u0026lt;100%)\u003c\/td\u003e \u003ctd\u003eExcellent\u003c\/td\u003e \u003ctd\u003ePPC: full MeOH compatibility.\u003c\/td\u003e \u003c\/tr\u003e \u003ctr\u003e \u003ctd\u003eEthyl acetate\u003c\/td\u003e \u003ctd\u003eExcellent\u003c\/td\u003e \u003ctd\u003ePPC: full EtOAc compatibility for LLE.\u003c\/td\u003e \u003c\/tr\u003e \u003ctr\u003e \u003ctd\u003eDMSO\u003c\/td\u003e \u003ctd\u003eExcellent\u003c\/td\u003e \u003ctd\u003ePPC: compatible for compound library storage.\u003c\/td\u003e \u003c\/tr\u003e \u003ctr\u003e \u003ctd\u003eAqueous buffers \/ plasma\u003c\/td\u003e \u003ctd\u003eExcellent\u003c\/td\u003e \u003ctd\u003ePPC inert across pH 2–12.\u003c\/td\u003e \u003c\/tr\u003e \u003ctr\u003e \u003ctd\u003eDichloromethane\u003c\/td\u003e \u003ctd\u003eNot Compatible\u003c\/td\u003e \u003ctd\u003eCauses cracking; do not use.\u003c\/td\u003e \u003c\/tr\u003e \u003ctr\u003e \u003ctd\u003eCold storage (—80°C DMSO)\u003c\/td\u003e \u003ctd\u003eExcellent\u003c\/td\u003e \u003ctd\u003ePPC: cold-temperature flexibility for frozen compound plates.\u003c\/td\u003e \u003c\/tr\u003e \u003ctr\u003e \u003ctd\u003eTrichloroacetic acid (TCA)\u003c\/td\u003e \u003ctd\u003eGood\u003c\/td\u003e \u003ctd\u003ePPC: compatible with TCA protein precipitation.\u003c\/td\u003e \u003c\/tr\u003e \u003c\/tbody\u003e \u003c\/table\u003e \u003ch2\u003eClinical \u0026amp; Research Laboratory Applications\u003c\/h2\u003e \u003cp\u003eCaplugs® Evergreen 1.0 mL tapered-bottom PPC deep well microplates serve bioanalytical, DMPK, forensic toxicology, and clinical chemistry laboratories performing LC-MS\/MS sample preparation in automated 96-well format. PPC is the material of choice for deep well LC-MS sample prep because its full organic solvent compatibility withstands acetonitrile and methanol protein precipitation, organic phase extraction in LLE, and SPE organic eluent collection without the cracking and analyte contamination risk that occurs when acetonitrile contacts PS deep well plates. Bioanalytical laboratories performing drug and metabolite quantitation in plasma by LC-MS\/MS use 96-well PPC deep well plates as the primary sample preparation vessel in protein precipitation workflows: plasma is dispensed into the deep well plate, acetonitrile is added at a 2:1 ratio, the plate is mixed and centrifuged, and the supernatant is transferred directly from the deep well plate to a 96-well injection plate for LC-MS analysis. \u003c\/p\u003e \u003ch2\u003eU.S. Manufacturing, Quality \u0026amp; Institutional Procurement\u003c\/h2\u003e \u003cp\u003eCaplugs® Evergreen products are manufactured in the United States under ISO 9001 quality management from FDA-compliant, food-contact-grade resins. BPA-free, phthalate-free, and latex-free, with material-disclosure documentation supporting CAP, CLIA, and ISO 15189 laboratory accreditation audits.\u003c\/p\u003e \u003cp\u003eLabSupplies.com is an authorized dealer for the full Caplugs Evergreen catalog and ships directly from USA inventory — typically same business day for stocking SKUs. We offer below retail pricing on volume orders, tiered institutional and academic pricing, and direct support for grant-funded laboratories and government procurement channels. Lab managers and procurement officers can \u003ca href=\"#request-sample\"\u003erequest a written quote or speak with a product specialist\u003c\/a\u003e directly from our sales engineering team.\u003c\/p\u003e \u003ch2\u003eFrequently Asked Questions\u003c\/h2\u003e \u003ch3\u003eIs the deep well microplate Sterile?\u003c\/h3\u003e \u003cp\u003eYes, sterile — packed 5\/Bag.\u003c\/p\u003e \u003ch3\u003eWhat is the chemical compatibility advantage of PPC for LC-MS sample prep?\u003c\/h3\u003e \u003cp\u003ePPC provides full compatibility with acetonitrile, methanol, and ethyl acetate — the primary extraction and precipitation solvents in LC-MS sample preparation. PS deep well plates show crazing and potential analyte contamination with prolonged acetonitrile contact (protein precipitation) and are not suitable for ethyl acetate-based LLE. PPC eliminates this risk. Choose PS when your workflow uses only aqueous reagents or brief organic contact (\u0026lt; 30 min acetonitrile), and PPC for any protocol with extended organic solvent contact.\u003c\/p\u003e \u003ch3\u003eWhat is the difference between Tapered  and Chamfered (222-8668-08C) deep well geometries?\u003c\/h3\u003e \u003cp\u003eTapered (conical tip): narrower base concentrates the sample volume at the well tip for maximum recovery of small residual volumes after centrifugation — important for maximizing sample recovery in protein precipitation and LLE. Chamfered (beveled angle): angled well bottom guides the final liquid to the center of the well base for complete liquid handler tip aspiration without residual corners — preferred on automation platforms where the robotic tip needs to aspirate the well to near-dryness. The 2.0 mL chamfered well also provides more volume for higher-ratio extraction protocols.\u003c\/p\u003e \u003cscript type=\"application\/ld+json\"\u003e{\"@context\": \"https:\/\/schema.org\/\", \"@type\": \"Product\", \"name\": \"Caplugs® Evergreen 222-8664-08N | 96-Well Deep Well Microplates, Tapered Bottom, 1.0 mL\/Well, Sterile — PPC, Natural, 5\/Bag\", \"sku\": \"222866408NE1\", \"mpn\": \"222-8664-08N\", \"brand\": {\"@type\": \"Brand\", \"name\": \"Caplugs® Evergreen\"}, \"manufacturer\": {\"@type\": \"Organization\", \"name\": \"Caplugs® Evergreen\", \"address\": \"USA\"}, \"material\": \"Polypropylene Copolymer (PPC)\", \"color\": \"Natural\", \"image\": \"https:\/\/prod-cp-cdn-images.azureedge.net\/catalog\/92300\/CB133AD1-CB0C-4B1A-9B7F-8FD51EDA3E77\/290-8553-08N.png\", \"description\": \"Caplugs® Evergreen 222-8664-08N: 96-Well Deep Well Microplates, Tapered Bottom, 1.0 mL\/Well, Sterile, PPC, Natural, 5\/Bag. MADE IN USA, authorized dealer.\", \"additionalProperty\": [{\"@type\": \"PropertyValue\", \"name\": \"Wells\", \"value\": \"96\"}, {\"@type\": \"PropertyValue\", \"name\": \"Well Bottom\", \"value\": \"Tapered\"}, {\"@type\": \"PropertyValue\", \"name\": \"Well Volume\", \"value\": \"1.0 mL\"}, {\"@type\": \"PropertyValue\", \"name\": \"Material\", \"value\": \"Polypropylene Copolymer (PPC)\"}, {\"@type\": \"PropertyValue\", \"name\": \"Sterility\", \"value\": \"Sterile\"}, {\"@type\": \"PropertyValue\", \"name\": \"Pack\", \"value\": \"5\/Bag\"}, {\"@type\": \"PropertyValue\", \"name\": \"Origin\", \"value\": \"USA\"}], \"offers\": {\"@type\": \"Offer\", \"priceCurrency\": \"USD\", \"price\": \"93.73\", \"availability\": \"https:\/\/schema.org\/InStock\", \"url\": \"https:\/\/labsupplies.com\/products\/222-8664-08n-deep-well-microplate\"}}\u003c\/script\u003e \u003cscript type=\"application\/ld+json\"\u003e{\"@context\": \"https:\/\/schema.org\/\", \"@type\": \"FAQPage\", \"mainEntity\": [{\"@type\": \"Question\", \"name\": \"Is the 222-8664-08N deep well microplate Sterile?\", \"acceptedAnswer\": {\"@type\": \"Answer\", \"text\": \"Yes, sterile — packed 5\/Bag.\"}}, {\"@type\": \"Question\", \"name\": \"What is the chemical compatibility advantage of PPC for LC-MS sample prep?\", \"acceptedAnswer\": {\"@type\": \"Answer\", \"text\": \"PPC provides full compatibility with acetonitrile, methanol, and ethyl acetate — the primary extraction and precipitation solvents in LC-MS sample preparation. PS deep well plates show crazing and potential analyte contamination with prolonged acetonitrile contact (protein precipitation) and are not suitable for ethyl acetate-based LLE. PPC eliminates this risk. Choose PS when your workflow uses only aqueous reagents or brief organic contact (\u003c 30 min acetonitrile), and PPC for any protocol with extended organic solvent contact.\"}}, {\"@type\": \"Question\", \"name\": \"What is the difference between Tapered (222-8664-08N) and Chamfered (222-8668-08C) deep well geometries?\", \"acceptedAnswer\": {\"@type\": \"Answer\", \"text\": \"Tapered (conical tip): narrower base concentrates the sample volume at the well tip for maximum recovery of small residual volumes after centrifugation — important for maximizing sample recovery in protein precipitation and LLE. Chamfered (beveled angle): angled well bottom guides the final liquid to the center of the well base for complete liquid handler tip aspiration without residual corners — preferred on automation platforms where the robotic tip needs to aspirate the well to near-dryness. The 2.0 mL chamfered well also provides more volume for higher-ratio extraction protocols.\"}}]}\u003c\/script\u003e","brand":"Caplugs® Evergreen","offers":[{"title":"Default Title","offer_id":48568506974440,"sku":"222866408NE1","price":93.73,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0694\/5361\/1240\/files\/290-8553-08N_7cca7074-1263-4ed1-931c-b5670b2b6a33.png?v=1779115395","url":"https:\/\/labsupplies.com\/products\/222-8664-08n-deep-well-microplate","provider":"LabSupplies.com","version":"1.0","type":"link"}